Depression increases the onset of cardiovascular disease over and above other determinants in older primary care patients, a cohort study

Marwijk, Harm van; Kooy, K.G. van der; Stehouwer, Coen D. A.; Beekman, Aartjan T.F.; Hout, Hein van

doi:10.1186/s12872-015-0036-y

Cited by 34 publications

(22 citation statements)

References 28 publications

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“…The literature showed that cardiovascular diseases were associated with a reduced in physical and mental dimensions of HRQoL [36]. In addition, a strong association was found between depression and cardiovascular diseases [37]. So we could have expected in our study a significant impact of pattern B multimorbidity score on mental HRQoL.…”

Section: Discussionmentioning

confidence: 66%

Effect of Multimorbidity on Health-Related Quality of Life in Adults Aged 55 Years or Older: Results from the SU.VI.MAX 2 Cohort

et al. 2016

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IntroductionMultimorbid chronic diseases are usually considered separately in trials. Here, we aimed to describe overall multimorbidity patterns in adults aged 55 years or older and assess their effect on health-related quality of life (HRQoL).MethodsWe used data for 5,647 participants included in the SUpplémentation en VItamines et Minéraux AntioXydants 2 (SU.VI.MAX 2) population-based trial. HRQoL was assessed by the French versions of the Medical Outcome Study Short Form 36 and the Duke Health Profile. An exploratory factor analysis was used to determine multimorbidity patterns, and a multimorbidity score for each resulting pattern was calculated. Adjusted multiple linear regression was used to examine the association between the identified multimorbidity and HRQoL scores by gender and for each age group (55–59, 60–64, 65–69, ≥ 70 years).ResultsMore than 63% of the sample reported two or more chronic conditions (from 55.8% for those 55–59 years to 74.4% for those ≥ 70 years). Multimorbidity was more common among women than men (67.3% vs 60%). Two different multimorbidity patterns were identified. Pattern A was represented mainly by mental illness and bone impairments. Pattern B was represented mainly by cardiovascular and metabolic disorders. After adjusting for covariates, a high pattern A score was associated with reduced HRQoL for the physical and mental components of each HRQoL questionnaire, and a high pattern B score was associated with reduced HRQoL for only the physical component of each questionnaire. These multimorbidity scores affected HRQoL differently by age group.ConclusionOur study used a novel methodological approach to account for multimorbidity patterns in determining the link with chronic conditions. These multimorbidity scores (counted and weighted) can be used in clinical research to control for the effect of multimorbidity on patients’ HRQoL and may be useful for clinical practice.Clinical Trial RegistrationClinicaltrial.gov (number NCT00272428).

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Section: Discussionmentioning

confidence: 66%

Effect of Multimorbidity on Health-Related Quality of Life in Adults Aged 55 Years or Older: Results from the SU.VI.MAX 2 Cohort

et al. 2016

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“…Depression is an independent risk factor for CVD in elderly people. 52 According to Garfield et al, 53 approximately 10% of people aged over 65 years suffer from depression. This study confirmed the occurrence of depressive symptoms in a similar proportion of elderly population.…”

Section: Discussionmentioning

confidence: 99%

The prevalence of risk factors for cardiovascular diseases among Polish surgical patients over 65 years

Kołtuniuk

Rosińczuk

2016

CIA

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BackgroundCardiovascular diseases (CVDs) are the leading cause of mortality among adults in Poland. A number of risk factors have significant influence on CVD incidence. Early identification of risk factors related to our lifestyle facilitates taking proper actions aiming at the reduction of their negative impact on health.AimThe aim of the study was to compare the prevalence of CVD risk factors between patients aged over 65 years and patients of other age groups in surgical wards.Material and methodsThe study was conducted for assessment and finding the distribution of major risk factors of CVD among 420 patients aged 18–84 years who were hospitalized in surgical wards. Interview, anthropometric measurements, blood pressure, and fasting blood tests for biochemical analysis were conducted in all subjects. Statistical analysis of the material was performed using Student’s t-test, chi-square test, Fisher’s exact test, Mann–Whitney U-test, and analysis of variance.ResultsWhile abdominal obesity (83.3%), overweight and obesity (68%), hypertension(65.1%), hypercholesterolemia (33.3%), and low level of physical activity (29.1%) were the most common CVD risk factors among patients over 65 years old, abdominal obesity (36.2%), overweight and obesity (36.1%), and current smoking were the most common CVD risk factors among patients up to the age of 35. In the age group over 65, the least prevalent risk factors for CVD were diabetes mellitus (14.8%), depressive episodes (13.6%), abuse of alcohol (11.4%), and smoking (7.8%). In the group under 35 years, we have not reported any cases of hypercholesterolemia and a lesser number of patients suffered from diabetes and HTN.ConclusionDistribution of the major risk factors for CVD is quite high in the adult population, especially in the age group over 65, which can result in serious problems of health and increased rates of chronic diseases, especially CVDs.

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“…18,[72][73][74][75][76] The EZOP Poland study showed that women more often show symptoms of depression. 67 The present study confirmed this dependence.…”

Section: Discussionmentioning

confidence: 99%

The influence of gender on selected risk factors for chronic non-communicable diseases in patients hospitalized in surgical wards: A cross-sectional study

Kołtuniuk¹,

Rosińczuk²

2018

Adv Clin Exp Med

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Depression increases the onset of cardiovascular disease over and above other determinants in older primary care patients, a cohort study

Cited by 34 publications

References 28 publications

Effect of Multimorbidity on Health-Related Quality of Life in Adults Aged 55 Years or Older: Results from the SU.VI.MAX 2 Cohort

Effect of Multimorbidity on Health-Related Quality of Life in Adults Aged 55 Years or Older: Results from the SU.VI.MAX 2 Cohort

The prevalence of risk factors for cardiovascular diseases among Polish surgical patients over 65 years

The influence of gender on selected risk factors for chronic non-communicable diseases in patients hospitalized in surgical wards: A cross-sectional study

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