Depression is a frequent co‐morbidity in patients with acne inversa

Kurek, Agata; Peters, Eva M.J.; Sabat, Robert; Sterry, Wolfram; Schneider‐Burrus, Sylke

doi:10.1111/ddg.12067

Cited by 74 publications

(107 citation statements)

References 43 publications

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“…It was further demonstrated that depression level is undoubtedly linked to HS clinical stage. Similar findings were presented by Matusiak et al [24] , with 21% of patients with HS having coexistence of depression [see also 25,26 ].…”

Section: Discussionsupporting

confidence: 86%

Quality of Life and Psychosocial Implications in Patients with Hidradenitis Suppurativa

et al. 2016

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Background: Hidradenitis suppurativa (HS) is a long-term skin disorder associated with high levels of psychological distress and significant life impact. Objective: To evaluate the quality of life, depression, anxiety, loneliness, and self-esteem in patients with HS. Methods: Ninety-four patients with HS were enrolled in the study. The quality of life, depression, anxiety, loneliness, and self-esteem of the patients were assessed using the Dermatology Life Quality Index (DLQI), the Hospital Anxiety and Depression Scale (HADS), the UCLA Loneliness Scale (UCLA-Version 3), and the Rosenberg Self-Esteem Scale (RSES), respectively. Results: The DLQI mean score was 11.43 ± 6.61 in patients with HS. The patients with HS presented statistically significantly higher anxiety (6.41 ± 3.31 vs. 5.00 ± 1.59, p < 0.001), depression (5.45 ± 2.79 vs. 4.16 ± 1.54, p < 0.001), and loneliness and social isolation scores (42.86 ± 8.63 vs. 35.57 ± 6.17, p < 0.001) and lower self-esteem scores (18.91 ± 1.79 vs. 19.77 ± 2.53, p = 0.008) than the healthy controls. Conclusions: HS is a distressing, recurrent disease that impairs quality of life. We can suggest services that allow an integrated approach, which includes psychosocial support, offering the patients relief from isolation and an opportunity to share common experiences.

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Section: Discussionsupporting

confidence: 86%

Quality of Life and Psychosocial Implications in Patients with Hidradenitis Suppurativa

et al. 2016

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“…The prevalence of depression is higher among people with HS compared to those with other dermatological conditions [14•, 28–30]. In the Danish self-report study, 48% of the ambulatory cohort with HS reported current or former depression diagnosed by a psychiatrist [15• •].…”

Section: Hs and Depressionmentioning

confidence: 99%

“…Pro-inflammatory cytokines in HS may mediate depression [38]. A case-control study of 45 German study subjects with HS found that the presence of inflammatory markers (C-reactive protein) were associated with higher depression scores on the Hospital Anxiety and Depression Scale [28•]. The authors concluded that inflammation in HS could lead to depression onset [28•].…”

Section: Hs and Depressionmentioning

confidence: 99%

Pain, Psychological Comorbidities, Disability, and Impaired Qualify of Life in Hidradenitis Suppurativa

Patel

Hoffman

Buse

et al. 2017

Curr Pain Headache Rep

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Purpose of Review Hidradenitis suppurativa (HS) is a chronic, painful dermatologic disease characterized by recurrent inflammatory nodules and abscesses of intertriginous areas such as the axilla and groin. People with HS suffer from greater pain and associated psychological comorbidities, including depression, anxiety, disability, and impairments in quality of life (QoL), compared to those with other dermatologic conditions. Our review focuses on the occurrence of pain and these relationships. Recent Findings The existing literature indicates that acute and chronic pain, depression, anxiety, and disability all contribute to poor quality of life in individuals with HS. Despite the central role of pain and distress in the presentation of HS, few studies have empirically evaluated the impact of pain and gaps remain in the existing psychosocial literature. There are no formal guidelines for treating HS-specific pain or psychological comorbidities. Summary The results of this review show a clear and pressing need to develop treatment recommendations and effective interventions for addressing acute and chronic pain, psychological comorbidities, disability, and impaired quality of life among people with HS. This review outlines a multidisciplinary approach to treating and managing pain and psychological comorbidities.

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“…42,43 Impaired sexual health, interpersonal relationship problems, emotional burden, feelings of lack of control, and depression are all found in disproportionate rates in patients with HS. [44][45][46] This finding is not surprising given the private and embarrassing nature of this disease, which is characterized by painful, often malodorous eruptions of intimate body parts.…”

Section: Discussionmentioning

confidence: 94%

Hidradenitis suppurativa is a systemic disease with substantial comorbidity burden: A chart-verified case-control analysis

Shlyankevich

Chen

Kim

et al. 2014

Journal of the American Academy of Dermatology

256

265

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Depression is a frequent co‐morbidity in patients with acne inversa

Abstract: Patients with AI have a higher risk of developing depression. Physicians should be alert to the possible development of depression when treating patients with this disorder.

Cited by 74 publications

References 43 publications

Quality of Life and Psychosocial Implications in Patients with Hidradenitis Suppurativa

Quality of Life and Psychosocial Implications in Patients with Hidradenitis Suppurativa

Pain, Psychological Comorbidities, Disability, and Impaired Qualify of Life in Hidradenitis Suppurativa

Hidradenitis suppurativa is a systemic disease with substantial comorbidity burden: A chart-verified case-control analysis

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