Depression may be a risk factor for coronary heart disease in midlife women &lt;65 years: A 9-year prospective cohort study

Jiang, Xuezhi; Asmaro, Ragad; O’Sullivan, David; Modi, Jaymin; Budnik, Elizabeth; Schnatz, Peter F.

doi:10.1016/j.ijcard.2018.05.085

Cited by 13 publications

(10 citation statements)

References 11 publications

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“…By middle age, women with clinical depression have double the risk of having a heart attack or stroke in the following 18 years compared to women without [20]. The influence of CMDs on cardiovascular risk in women aged under 65 years is evident within a decade [21]. As depression and anxiety are both largely heterogeneous conditions comprising different severities, symptom subtypes and combinations, it is difficult to identify the CVD risk each confers.…”

Section: Introductionmentioning

confidence: 99%

How Does Mental Health Impact Women's Heart Health?

O’Neil

Russell

Murphy

2021

Heart, Lung and Circulation

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From adolescence until old age, women are more vulnerable to common mental disorders (CMDs; depression and anxiety) than men at all stages of the life course. By middle age, women who have clinical depression are at twice the risk of having an incident cardiovascular disease (CVD) than those without. This has important implications for the way we prevent, identify and treat both CMDs and coronary heart disease in women. In this paper, we discuss the various genetic, biological, ethnic/racial, and psychological pathways by which women's vulnerability to CMDs elevate their CVD risk and recovery from a cardiac event. We review the evidence from trials that have, to date, failed to show that treating depression can reduce or delay the onset or recurrence of CVD events, especially for female patients. We discuss the value of lifestyle-based therapies for treating depression, to which women may be more responsive, and finish by discussing how population-based approaches including risk factor assessment could be tailored to consider these factors.

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Section: Introductionmentioning

confidence: 99%

How Does Mental Health Impact Women's Heart Health?

O’Neil

Russell

Murphy

2021

Heart, Lung and Circulation

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“…In addition, a church-based longitudinal intervention of mid-life and older African Americans showed that low life satisfaction is positively associated with the risk of cardiovascular disease (Mendez et al, 2018). Furthermore, patients with depression are at an increased risk of developing coronary heart disease (Belialov, 2017; Jiang et al, 2018), and the association between anxiety and cardiovascular disease has been demonstrated in cross-sectional, etiological, and prognostic studies (Tully et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Influence of Life Satisfaction on Quality of Life: Mediating Roles of Depression and Anxiety Among Cardiovascular Disease Patients

et al. 2020

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The present study aimed to determine the mediating effects of depression and anxiety on the association between life satisfaction and quality of life. We used the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder Scale (GAD-7), and EuroQol Five Dimensions Questionnaire (EQ-5D) to measure depression, anxiety, and quality of life, respectively. A single question was used to measure the life satisfaction of participants. Life satisfaction was significantly related with depression ( r = −0.17), anxiety ( r = −0.18), and quality of life ( r = 0.19). Depression and anxiety were also related to quality of life. Depression and anxiety had full mediating effects (β = −0.274; β = −0.208) on the association between life satisfaction and quality of life. For those with poor life satisfaction, people were more likely to have high level of depression and anxiety, which in turn experienced poor quality of life.

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“…Patients with depressive disorders were reported to have a higher serum concentration of inflammatory markers, including interleukin (IL)-6, tumor necrosis factor (TNF)-α and IL-1β, compared with those without depressive disorders [3,4]. Depression was also found to be associated with chronic diseases related to inflammation, including chronic obstructive pulmonary disease [5,6], coronary arterial disease [7,8,9], heart failure [10], dementia [11], and arthritis [12].…”

Section: Introductionmentioning

confidence: 99%

Depression increases the risk of rotator cuff tear and rotator cuff repair surgery: A nationwide population-based study

Kuo

Chen

et al. 2019

PLoS ONE

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BackgroundChronic inflammation is known to be associated with both rotator cuff tears (RCTs) and depression. However, no epidemiological studies with a longitudinal follow-up have been performed to prove this association. We aimed to investigate whether depressed patients had an elevated risk of RCT and subsequent repair surgery compared with those without depression.MethodsThis retrospective cohort study comprised of patients diagnosed with depression between 2000 and 2010 (depression cohort) and patients without depression (non-depression cohort, 1:2 age and sex matched). The risk of RCT and rotator cuff repair surgery were determined during a 13-year follow-up (2000–2013) between these two cohorts.ResultsThis study included 26,868 patients with depression and 53,736 patients without depression. The incidence of RCT was 648 and 438 per 100,000 person-years in the depression and non-depression cohorts, respectively. The adjusted hazard ratio (HR) was 1.46 (95% confidence interval [CI], 1.36–1.57) for depressed patients. The incidence of rotator cuff repair surgery was 28 and 18 per 100,000 person-years in the depression and non-depression cohorts, respectively. Depressed patients also had a significantly increased risk of subsequent rotator cuff repair surgery (adjusted HR = 1.46; 95% CI, 1.04–2.06).ConclusionThe present study showed that depression was associated with an ncreased risk of rotator cuff tear and rotator cuff repair surgery.

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Depression may be a risk factor for coronary heart disease in midlife women <65 years: A 9-year prospective cohort study

Cited by 13 publications

References 11 publications

How Does Mental Health Impact Women's Heart Health?

How Does Mental Health Impact Women's Heart Health?

Influence of Life Satisfaction on Quality of Life: Mediating Roles of Depression and Anxiety Among Cardiovascular Disease Patients

Depression increases the risk of rotator cuff tear and rotator cuff repair surgery: A nationwide population-based study

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Depression may be a risk factor for coronary heart disease in midlife women <65 years: A 9-year prospective cohort study

Cited by 13 publications

References 11 publications

How Does Mental Health Impact Women's Heart Health?

How Does Mental Health Impact Women's Heart Health?

Influence of Life Satisfaction on Quality of Life: Mediating Roles of Depression and Anxiety Among Cardiovascular Disease Patients

Depression increases the risk of rotator cuff tear and rotator cuff repair surgery: A nationwide population-based study

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Depression may be a risk factor for coronary heart disease in midlife women <65 years: A 9-year prospective cohort study