Depression Symptom Trajectories Among Mothers Living with HIV in Rural Uganda

Familiar, Itziar; Sikorskii, Alla; Murray, Sarah; Ruiseñor-Escudero, Horacio; Nakasujja, Noeline; Korneffel, Clinton; Boivin, Michael J.; Bass, Judith

doi:10.1007/s10461-019-02465-0

Cited by 10 publications

(6 citation statements)

References 42 publications

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“…This study found that the track of depressive symptoms of young and middle-aged MSM within one-year after HIV-diagnosis is different in terms of severity and stability, which is consistent with previous studies for people living with HIV ( 23 , 32 ). The classification result of this study is consistent with Bonanno’s ( 22 ) view that psychological changes in groups after experiencing trauma follow different trajectories.…”

Section: Discussionsupporting

confidence: 92%

“…The non-depression group, the chronic-mild depression group, and the persistent moderate–severe depression group in our study are consistent with the recovery trajectory, the resilience trajectory, and the chronic dysfunction trajectory in Bonanno’s view, respectively. Among the three latent category groups, more than half of the patients (56.4%) were in the non-depression group, which is similar to the results from a longitudinal study on previous HIV-positive patients ( 32 , 33 ), but higher than the study of Heckman et al ( 34 ) in 105 older adults with HIV infection (31% non-depression) and Larsen et al ( 35 ) in 824 HIV-positive pregnant women (38.5% with persistent no/mild depressive symptoms). The young and middle-aged MSM included in this study were mostly employed (70.43%), single or without children in marital status (89.63%), with high monthly income [70.43% over 5,000 RMB/month (equal to 690 USD)].…”

Section: Discussionsupporting

confidence: 85%

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Trajectories of depressive symptoms in young and middle-aged men who have sex with men with new HIV-diagnosis: a 1-year prospective cohort study in Beijing, China

Li,

Liu,

Han

et al. 2023

Front. Public Health

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IntroductionDue to the sexual orientation and HIV diagnosis, young and middle-aged men who have sex with men (MSM) with new HIV-diagnosis may experience more depressive syndromes and face greater psychological stress. The study explored trajectories of depressive symptoms of young and middle-aged MSM within 1 year after new HIV-diagnosis and analyze the related factors.MethodsFrom January 2021 to March 2021, 372 young and middle-aged MSM who were newly diagnosed as HIV-infection were recruited in two hospitals in Beijing. Self-rating Depression Scale was used to measure the participants’ depressive symptom in 1st month, 3rd month, 6th month, 9th month and 12th month after HIV diagnosis. The latent class growth model was used to identify trajectories of the participants’ depressive symptoms. Multinomial logistic regression was used to analyse factors related with the trajectories.ResultsThree hundred and twenty-eight young and middle-aged MSM with new HIV-diagnosis completed the research. Depressive symptom in 328 young and middle-aged MSM was divided into three latent categories: non-depression group (56.4%), chronic-mild depression group (28.1%), and persistent moderate–severe depression group (15.5%). The participants assessed as non-depression (non-depression group) or mild depression (chronic-mild depression group) at the baseline were in a non-depression state or had a downward trend within one-year, and the participants assessed as moderate and severe depression (persistent moderate–severe depression group) at the time of diagnosis were in a depression state continuously within 1-year. Multinomial logistic regression analysis showed that, compared with the non-depression group, monthly income of 5,000 ~ 10,000 RMB (equal to 690 ~ 1,380 USD) was the risk factor for the chronic-mild depression group, and self-rating status being fair/good and self-disclosure of HIV infection were protective factors for the persistent moderate–severe depression group while HIV-related symptoms was the risk factor.ConclusionDepressive symptoms in young and middle-aged MSM is divided into three latent categories. Extra care must be given to young and middle-aged MSM assessed as moderate or severe depression at the time of HIV-diagnosis, especially to those who had poor self-rating health status, did not tell others about their HIV-infection and experienced HIV-related symptoms.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 85%

Trajectories of depressive symptoms in young and middle-aged men who have sex with men with new HIV-diagnosis: a 1-year prospective cohort study in Beijing, China

Li,

Liu,

Han

et al. 2023

Front. Public Health

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“…Both diagnostic and screening tools were used to assess depression among different populations in Uganda ( Table 1 ). The tools used included: (i) Depression sub-section of the Hopkins Symptom Checklist (DHSCL) ( n = 34, 26.8%) [ 35 , 55 , 61 , 63 , 65 – 68 , 71 , 73 , 74 , 79 – 82 , 84 , 92 , 100 , 108 , 110 , 111 , 113 , 125 , 135 , 136 , 138 , 140 , 141 , 144 , 147 , 151 , 155 , 166 ], (ii) Patient Health Questionnaire (PHQ) ( n = 33, 26.0%) [ 16 , 21 , 32 , 34 , 36 , 37 , 52 , 86 , 88 – 90 , 93 , 98 , 99 , 101 , 102 , 112 , 116 – 118 , 120 – 123 , 126 – 128 , …”

Section: Resultsmentioning

confidence: 99%

“…Depression was screened or diagnosed in the following study groups in Uganda: (i) individuals living with HIV ( n = 43) [ 15 , 34 , 60 , 64 , 68 , 70 – 73 , 79 , 81 , 82 , 85 – 91 , 93 – 96 , 98 – 105 , 112 – 114 , 117 , 119 , 123 , 127 , 128 , 130 , 132 , 133 , 136 , 141 – 143 , 145 , 148 – 150 , 160 ], (ii) females only ( n = 25) [ 16 , 31 , 35 , 52 , 59 , 73 , 79 , 97 , 113 , 116 , 134 , 139 , 144 , 158 , 166 , 170 ], including seven studies among pregnant or postpartum women [ 53 , 59 , 73 , 97 , ...…”

Section: Resultsmentioning

confidence: 99%

Prevalence of depression in Uganda: A systematic review and meta-analysis

Kaggwa

Najjuka²,

Bongomin³

et al. 2022

PLoS ONE

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Background Depression is one of the most studied mental health disorders, with varying prevalence rates reported across study populations in Uganda. A systematic review and meta-analysis was carried out to determine the pooled prevalence of depression and the prevalence of depression across different study populations in the country. Methods Papers for the review were retrieved from PubMed, Scopus, PsycINFO, African Journal OnLine, and Google Scholar databases. All included papers were observational studies regarding depression prevalence in Uganda, published before September 2021. The Joanna Briggs Institute Checklist for Prevalence Studies was used to evaluate the risk of bias and quality of the included papers, and depression pooled prevalence was determined using a random-effects meta-analysis. Results A total of 127 studies comprising 123,859 individuals were identified. Most studies were conducted among individuals living with HIV (n = 43; 33.9%), and the most frequently used instrument for assessing depression was the Depression sub-section of the Hopkins Symptom Checklist (n = 34). The pooled prevalence of depression was 30.2% (95% confidence interval [CI]: 26.7–34.1, I2 = 99.80, p<0.001). The prevalence of depression was higher during the COVID-19 pandemic than during the pre-pandemic period (48.1% vs. 29.3%, p = 0.021). Refugees had the highest prevalence of depression (67.6%; eight studies), followed by war victims (36.0%; 12 studies), individuals living with HIV (28.2%; 43 studies), postpartum or pregnant mothers (26.9%; seven studies), university students (26.9%; four studies), children and adolescents (23.6%; 10 studies), and caregivers of patients (18.5%; six studies). Limitation Significantly high levels of heterogeneity among the studies included. Conclusion Almost one in three individuals in Uganda has depression, with the refugee population being disproportionately affected. Targeted models for depression screening and management across various populations across the country are recommended. Trial registration Protocol registered with PROSPERO (CRD42022310122).

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“…In a similar vein, another study found that social and environmental adversities in childhood and externalizing disorders are associated with an increased risk of suicidal ideation in adolescence and young adulthood ( Orri et al., 2022 ). This study revealed how individual, family, and environmental factors in childhood are likely to harm an individual’s future ( Familiar et al., 2019 ; Familiar et al., 2020 ). Additionally, in investigating the influence of early development on preschool cognitive and behavioral outcomes, one study showed that mental development assessed at 1 year of age significantly predicts preschool outcomes at age five; the children with poor mental development at 1 year of age displayed the lowest cognitive and behavioral development at age five ( Hsiao & Richter, 2014 ).…”

Section: Discussionmentioning

confidence: 94%

Is Neurodevelopmental Assessment in Early Childhood Predictive of Performance Assessed Later in Childhood and Adolescence in Sub-Saharan Africa? A Systematic Review of the Literature

Zoumenou,

Bodeau-Livinec,

Chausseboeuf

et al. 2023

Archives of Clinical Neuropsychology

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Background Most neurodevelopmental tests used to assess child development in sub-Saharan Africa were developed in western or high-income countries, raising the question of their usefulness with African children. Objective This systematic review identified and synthesized key findings from studies measuring development in children in Sub-Saharan Africa in early childhood and again at school age, to assess neurocognitive associations longitudinally from infancy through middle childhood. Methods The study was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method, selecting articles referenced in the PubMed, PsycInfo, and Embase databases using the following inclusion criteria: published between 2000 and 2022, written in French or English, and presenting results dealing with the objective assessment of child’s neurodevelopment. All articles were registered in the Zotero reference manager and analyzed by title, abstract, and full text. Results Several of the seven selected studies confirmed that attention and working memory in infancy can predict children’s neurocognitive performance, including mathematical ability, at school age. In two of the studies, children with poor mental development at 1 year of age are more likely to present with poorer behavioral development at school age, including learning difficulties in school and risk for grade repetition. Conclusion Cognitive ability assessed in early childhood is strongly associated with performance at school age in cohorts of African children followed longitudinally. Even with assessments adapted cross-culturally, infants and preschoolers at risk for poor developmental outcomes can be identified to better receive strategic early interventions to enhance their development.

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Depression Symptom Trajectories Among Mothers Living with HIV in Rural Uganda

Cited by 10 publications

References 42 publications

Trajectories of depressive symptoms in young and middle-aged men who have sex with men with new HIV-diagnosis: a 1-year prospective cohort study in Beijing, China

Trajectories of depressive symptoms in young and middle-aged men who have sex with men with new HIV-diagnosis: a 1-year prospective cohort study in Beijing, China

Prevalence of depression in Uganda: A systematic review and meta-analysis

Is Neurodevelopmental Assessment in Early Childhood Predictive of Performance Assessed Later in Childhood and Adolescence in Sub-Saharan Africa? A Systematic Review of the Literature

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