Depression with pain co morbidity effect on quality of life among HIV positive patients in Uganda: a cross sectional study

Mwesiga, Emmanuel Kiiza; Mugenyi, Levi; Nakasujja, Noeline; Moore, Shirley; Kaddumukasa, Mark; Sajatovic, Martha

doi:10.1186/s12955-015-0403-5

Cited by 27 publications

(22 citation statements)

References 43 publications

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“…Patients who have pain may have depression with longer duration and greater severity compared to those do not [31]. Among HIV patients, especially those who are symptomatic or in AIDS stage, they may consider pain as a symptom of depression or as an aversion which triggers an extreme negative reaction such as depression [32,33]. Conversely, the depressive disorder can forecast the development of pain due to the somatization of emotional problems [34].…”

Section: Discussionmentioning

confidence: 99%

Socioeconomic Vulnerability to Depressive Symptoms in Patients with Chronic Hepatitis B

Le²,

Dang

et al. 2019

IJERPH

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Depression is considered one of the most prevalent psychiatric disorders among patients with hepatitis B virus (HBV)-related liver disease and has adverse effects on the disease progression. However, there is a scarcity of studies contributing to the assessement of depression in hepatitis B patients. There is also little research into risk factors, particularly underlying socio-economic factors in Vietnam where the prevalence of hepatitis B is high. This study aimed to examine depression and identify whether differences in socio-economic status is related to the level of depression amongst chronic hepatitis B patients. A cross-sectional study was conducted on 298 patients with chronic hepatitis B at The Chronic Hepatitis Clinic in the Viet-Tiep Hospital, Hai Phong, Vietnam. The Patient Health Questionnaire-9 (PHQ-9) and EuroQol-5 dimensions-5 levels (EQ-5D-5L) were used to assess the severity of depression and health-related quality of life (HRQOL). Of chronic hepatitis B patients, 37.5% experienced depressive symptoms and most of them suffered minimal depressive symptoms (31.4%). According to the result of the multivariate logistic regression model, we found that higher age, lower income level, unemployement, living with spouse/partners were positively associated with having depression. Furthermore, having physical health problems and lower health-related quality of life were also related to a higher risk of depression. We recommend family support, financial support and active participation in consultation should be conducted during treatment to improve the quality of life and the emotional state of HBV patients.

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Section: Discussionmentioning

confidence: 99%

Socioeconomic Vulnerability to Depressive Symptoms in Patients with Chronic Hepatitis B

Le²,

Dang

et al. 2019

IJERPH

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“…Patients who undergo pain may have depression for a longer period and with greater severity compared to those who do not [42]. HIV patients, especially those who are in a symptomatic or AIDS stage, may consider pain as a symptom of depression or as an aversion that triggers an extremely negative reaction such as depression [41,43]. Conversely, the depressive disorder can forecast the development of pain due to the somatization of emotional problems [44].…”

Section: Discussionmentioning

confidence: 99%

Depression and Quality of Life among Patients Living with HIV/AIDS in the Era of Universal Treatment Access in Vietnam

Tran

Dang

Truong

et al. 2018

IJERPH

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Although antiretroviral treatment (ART) access has been universal in recent years, few studies have examined if this policy contributes to the mental health of the patients. This study assessed depression and its relations with health-related quality of life (HRQOL), which is defined as the status of general well-being, physical, emotional, and psychological, among HIV patients. A cross-sectional study was conducted in 482 patients at five outpatient clinics. Patient Health Questionnaire-9 (PHQ-9) and EuroQol-5 dimensions-5 levels (EQ-5D-5L) were used to assess the severity of depression and HRQOL. About one-fifth of patients reported symptoms of depression. According to the result of a multivariate logistic regression model, patients who had a lower number of CD4 cells at the start of ART, who received ART in the clinic without HIV counseling and testing (HCT) services, who had a physical health problem, and who experienced discrimination were more likely to have depression. Depression was associated with significantly decreased HRQOL. Depression is prevalent and significantly negatively associated with HRQOL of HIV/AIDS patients. We recommend screening for depression and intervening in the lives of depressed individuals with respect to those who start ART late, and we also recommend community-based behavioral change campaigns to reduce HIV discrimination.

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“…Understanding the intersection of mental health and substance use in the context of pain is vital for developing interventions aligned with the White House's National HIV/AIDS Strategy of improving health outcomes for PLHIV [21]. Further, identifying factors associated with pain may inform strategies that seek to improve quality of life and improve clinical outcomes among PLHIV [22,23]. One shared limitation of previous studies targeting pain and substance use among PLHIV was the inability to control for the peak-end phenomenon.…”

Section: Introductionmentioning

confidence: 99%

Factors associated with current and severe pain among people living with HIV: results from a statewide sample

et al. 2020

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Background People living with HIV (PLHIV) are more likely to suffer from pain compared to the general public. Pain often clusters with mental health symptoms and substance use. This study sought to evaluate mental health and substance use factors associated with any pain and severe pain intensities among PLHIV. Methods Data were derived from HIV+ adults (N = 733) recruited from community health centers across Florida who completed questionnaires regarding demographics, chronic pain, HIV clinical outcomes, mental health symptoms, and substance use information. Pain was assessed using the Brief Pain Inventory (BPI) short form. Multivariate logistic regression analysis was utilized to assess the relationship between selected covariates and pain. Results Approximately half (45.0%) of participants reported having any current pain while 16.1% reported severe pain. The odds of having any current pain were 2.49 (CI 95% 1.48, 4.18, p < 0.01) times greater among PLHIV reporting anxiety and 1.69 (CI 95% 1.11, 2.57, p = 0.01) times greater among PLHIV reporting PTSD compared to those without those factors. The odds of having severe pain were 2.03 (CI 95% 1.03, 4.01, p = 0.04) times greater among PLHIV reporting anxiety and 2.02 (CI 95% 1.26, 3.24, p < 0.01) times greater among female participants compared to PLHIV without those factors respectively. Factors including depression, alcohol consumption, and marijuana use were not statistically associated with any current pain nor with severe pain. Conclusion The relationship between pain and mental health is complex. Thus, future research is needed to determine if pain treatments may reduce mental health symptoms or if treatments can be targeted to address both issues simultaneously.

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Depression with pain co morbidity effect on quality of life among HIV positive patients in Uganda: a cross sectional study

Cited by 27 publications

References 43 publications

Socioeconomic Vulnerability to Depressive Symptoms in Patients with Chronic Hepatitis B

Socioeconomic Vulnerability to Depressive Symptoms in Patients with Chronic Hepatitis B

Depression and Quality of Life among Patients Living with HIV/AIDS in the Era of Universal Treatment Access in Vietnam

Factors associated with current and severe pain among people living with HIV: results from a statewide sample

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