Depressive and Anxiety Symptoms in Patients With Schizophrenia and Schizophreniform Disorder

Emsley, Robin; Oosthuizen, Piet; Joubert, André F.; Roberts, Mimi C.; Stein, Dan J.

doi:10.4088/jcp.v60n1105

Cited by 133 publications

(96 citation statements)

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“…Depressive symptoms are reported to occur particularly in the first episode and are more severe [32,33]. However, it is questionable whether sleep disturbances, psychomotor retardation, and attention problems in psychoses relate to depressive symptoms or to negative symptoms.…”

Section: Discussionmentioning

confidence: 99%

Characteristics of early psychosis

Schothorst

Emck

Engeland

2006

Comprehensive Psychiatry

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There is little research on characteristics related to course and prognosis of early-onset psychosis. The present article aims to advance our knowledge of this disorder for the purpose of proper diagnosis and treatment. It focuses on premorbid and prodromal characteristics, treatment history, symptoms and classifications, and differences between subgroups with affective and schizophrenic psychosis.A chart review was constructed to study a group of 129 subjects (12-18 years) with psychotic symptoms referred to the University Medical Center in Utrecht.The group was characterized by early-but nonspecific-treatment, developmental problems (mostly social), and clear prodromal symptoms. Drug abuse, depressive symptoms, and suicidal behavior were also frequent. Male sex, a relatively long prodromal phase, school problems, and drug abuse were more indicative of the schizophrenic subgroup. Introversion was characteristic for boys with schizophrenia. Classifications, however, were not stable.These findings suggest that early recognition of psychosis can be enhanced in health and youth care facilities. Careful examination of the prodromal phase seems helpful to differentiate between schizophrenic and affective psychosis. D

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Section: Discussionmentioning

confidence: 99%

Characteristics of early psychosis

Schothorst

Emck

Engeland

2006

Comprehensive Psychiatry

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“…Notably, depression and anxiety appear to share a number of phenotypic similarities with the negative symptom dimension of schizophrenia. However, anxiety and depression appear to be more strongly associated with the positive factor of schizophrenia than the negative factor ( [Emsley et al, 1999] and [Lysaker et al, 1995]), suggesting that negative symptom schizophrenia reflects a relative deficit in affect that is inconsistent with the experience of anxiety and depression. For example, Drake et al (2004) found that paranoia (a positive symptom) predicted elevated depression in schizophrenia and spectrum disorder patients.…”

Section: Relationship Of Schizophrenia With Mood and Anxiety Symptomsmentioning

confidence: 96%

Anxiety and depression symptoms in psychometrically identified schizotypy

Lewandowski

Barrantes‐Vidal

Nelson‐Gray

et al. 2006

Schizophrenia Research

186

122

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Abstract:The neurodevelopmental vulnerability for schizophrenia appears to be expressed across a dynamic continuum of adjustment referred to as schizotypy. This model suggests that nonpsychotic schizotypic individuals should exhibit mild and transient forms of symptoms seen in full-blown schizophrenia. Given that depression and anxiety are reported to be comorbid with schizophrenia, the present study examined the relationship of psychometrically defined schizotypy with symptoms of depression and anxiety in a college student sample (n = 1258). A series of confirmatory factor analyses indicated that a three-factor solution of positive schizotypy, negative schizotypy, and negative affect provided the best solution for self-report measures of schizotypy, anxiety, and depression. As hypothesized, the model indicated that symptoms of depression and anxiety are more strongly associated with the positive-symptom dimension of schizotypy than with the negative-symptom dimension. This is consistent with studies of schizophrenic patients and longitudinal findings that positive-symptom schizotypes are at risk for both mood and non-mood psychotic disorders, while negative-symptom schizotypes appear more specifically at risk for schizophrenia-spectrum disorders. chizotypy | schizophrenia | anxiety | depression | psychology

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“…33 Nevertheless, Emsley et al and Koreen et al pointed out to the optimistic outcomes of schizophrenia once it is accompanied by depressive features. 4,24 Oosthuizen et al, as well, confirmed the positive outcome of comorbid schizophrenia with depression and found that depression during psychosis differs from ICD-10 post-psychotic depressive disorder since the later carries poorer prognosis. 34 In an attempt to understand whether both depressed and non-depressed patients with schizophrenia differ in their demographic variables, multivariate analyses revealed no significant differences in age, gender, employment, and marital status, unlike primary depression where it is well-known that depressive disorders, overall, are more prevalent among elderly, female gender, unemployed, as well as nonmarried individuals.…”

Section: Resultsmentioning

confidence: 94%

“…2, 3 Depressive symptoms in schizophrenia have been measured using several sorts of assessment tools like the Positive and Negative Syndrome Scale (PANSS), 4 the Brief Psychiatric Rating Scale (BPRS), 5 and the Montgomry-Asperg Depression Rating Scale. 6 However, Calgary Depression Scale for Schizophrenia (CDSS) was designed specifically to detect depression among patients with schizophrenia.…”

Section: Introductionmentioning

confidence: 99%