2018
DOI: 10.1093/cid/ciy496
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Depressive Symptoms and Engagement in Human Immunodeficiency Virus Care Following Antiretroviral Therapy Initiation

Abstract: We included 1,057 HIV-infected adults, who contributed 2,424 person years. At ART initiation 30% of participants reported depressive symptoms. In multivariable analyses, recent depressive symptoms increased the risk of having a detectable viral load (RR 1.28, 95% CI 1.07, 1.53) over time. The association between depressive symptoms and missing an HIV visit (RR 1.20, 95% CI 1.05, 1.36) moved to the null after adjustment for pre-existing mental health conditions (RR 1.00, 95% CI 0.85, 1.18).

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Cited by 27 publications
(11 citation statements)
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“…Depressive disorder impairs QoL in PLWH 5 . It affects ART adherence, hindering viral control and immune restoration, and is associated with cognitive impairment and all-cause mortality 6 8 . In France, over a decade ago, the prevalence of depressive disorder was estimated at 28.1% in PLWH or 2 to 5 times greater than in the general population (GP), varying by HIV risk group 9 .…”
Section: Introductionmentioning
confidence: 99%
“…Depressive disorder impairs QoL in PLWH 5 . It affects ART adherence, hindering viral control and immune restoration, and is associated with cognitive impairment and all-cause mortality 6 8 . In France, over a decade ago, the prevalence of depressive disorder was estimated at 28.1% in PLWH or 2 to 5 times greater than in the general population (GP), varying by HIV risk group 9 .…”
Section: Introductionmentioning
confidence: 99%
“…[ 23 ] Furthermore, the existing evidence suggests that higher levels of depression among PLWH adversely impact outcomes across the HIV treatment cascade. [ 24 ]…”
Section: Discussionmentioning
confidence: 99%
“…Для ВІЛінфікованих характерний і такий психологічний стан, як саморуйнування. Були проведені наукові роботи, що підтвердили мультифакторну природу антивітальних тенденцій у поведінці ВІЛ-інфікованих, указуючи на те, що не тільки депресія є важливим фактором, що веде до суїцидальної поведінки, але й порушення сну (а саме термінальна інсомнія); ступінь особистісної ворожнечі (негативні відчуття і негативні оцінки людей і подій); тривожні розлади [7]. У цих складних умовах суспільство повинно створити систему громадської солідарності, що має гуманістичний характер.…”
Section: (104)2021 інфекційні хворобиunclassified