Depressive Symptoms and Neurocardiogenic Syncope in Children: A 2-Year Prospective Study

Hyphantis, Thomas; Pappas, Argiro-Irene; Vlahos, Antonios P.; Carvalho, André F.; Levenson, James L.; Kolettis, Theofilos M.

doi:10.1542/peds.2012-1379

Cited by 13 publications

(12 citation statements)

References 34 publications

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“…Although, other studies [6,7] evidenced a good prognosis in patients with NCS, we experienced a great impact on quality of life in patients and their families. In this group of patients we reported a major frequency of somatic and thought problems as skin problems, vomit, stomach problems, sleep problems and unusual thoughts compared with healthy subjects and of emotional problems as anxiety, depressive withdrawal and somatic complaints.…”

Section: Discussionmentioning

confidence: 69%

“…Some studies showed a high prevalence of psychiatric morbidity among syncope patients, with rates up to 80% in adult patients, but relevant data in children and adolescents are few [6,7].…”

Section: Introductionmentioning

confidence: 99%

“…Several earlier studies on patients with syncope have found significant deviations in behavior, in the development of psychopathological symptoms [7] and in the effects of pediatric syncope on health-related quality of life [6], but few studies have observed significant difference in behavior if compared with control group of healthy subjects [8,9].…”

Section: Introductionmentioning

confidence: 99%

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Dysfunctional Behaviors in Children and Adolescents with Neurocardiogenic Syncope

Capitello¹

2014

J Child Adolesc Behav

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Objective : We evaluate a large sample of children and adolescent with suspected neurocardiogenic syncope (NCS) and we compared the results with a healthy sample, with the aim to reveal a possible correlation between syncopal events and dysfunctional behaviors. Methods:A total number of ninety two patients with NCS (median age 14.7 years) were evaluated with Head-Up Tilt Test (HUTT) and psychological assessment at the same time. The results of the ninety two patients who underwent HUTT and completed psychological tests were compared with a normative group. The risk of psychosocial dysfunctions was assessed by using the standardized Italian version of the Child Behavior Checklist in Youth Self Report (YSR).Results: Compared with normative group, patients with NCS reported worse scores to the internalizing and total problem scales and to the syndrome scales of anxiety problems, depressive withdrawal problems, somatic complaints, social problems and thought problems. Conclusions:Patients with NCS present major emotional and behavioral dysfunctions than healthy sample. Our findings call for additional investigations on the possible pathophysiological association between psychosocial problems and the reflex mechanism that produces syncope. Furthermore, future clinical studies are necessary to plan an interventional strategy and optimize the clinical management.

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Section: Discussionmentioning

confidence: 69%

“…Some studies showed a high prevalence of psychiatric morbidity among syncope patients, with rates up to 80% in adult patients, but relevant data in children and adolescents are few [6,7].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Dysfunctional Behaviors in Children and Adolescents with Neurocardiogenic Syncope

Capitello¹

2014

J Child Adolesc Behav

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“…HypHantiS et al [153] reported an incidence of 35% in clinically significant depressive symptoms in children and adolescents with Neurocardiogenic Syncope, a 2.6-fold higher rate compared with healthy control subjects. Family functioning, as indicated by child-parent relationships and family cohesion, was associated with depressive symptomatology.…”

Section: Comorbiditiesmentioning

confidence: 99%

“…Several studies [153][154][155][156][157][158][159][160] in adults have shown that patients with syncope exhibit high levels of psychological distress, including anxiety and depression. HypHantiS et al [153] reported an incidence of 35% in clinically significant depressive symptoms in children and adolescents with Neurocardiogenic Syncope, a 2.6-fold higher rate compared with healthy control subjects.…”

Section: Comorbiditiesmentioning

confidence: 99%

Childhood Depression As Emerging Public Health Problem: A Systematic Review

Pimentel¹,

Júnior²,

Júnior³

et al. 2015

Int Arch Med

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As an important problem of public health, the childhood depression deserves special attention, in which the serious and long term consequences of the disease weigh to the childhood development. Taking this in consideration, the present study was based in the following research question: which practical contribution the actual scientific literature about childhood depression has to offer to clinicians and researchers? The aim of the present study was to evaluate the actual evidence concerning the different aspects (etiology/risk factors, diagnosis, treatment, prognostic and prevention) of childhood depression, with the purpose to systematize such evidences and to contribute with the knowledge about the problem. In way to reach this aim, it was performed a systematic review of articles about childhood depression, in the period from January first of 2010 to January 16 of 2014, in the databases PubMED, MEDLINE and SciELO. In the research, the following terms were used: "depression" (MeSH), "child" (MeSH) and "childhood depression" (Keyword). Of the 860 found studies, 76 met the eligibility criteria. The found studies covered a wide variety of aspects related to childhood depression, as diagnosis, treatment, prevention and prognostic. The actual scientific literature about the childhood depression converges to, directly or not, highlight the negative impacts of the depression disorders to the life quality of the children. Unfortunately, the found studies show that the childhood depression is a disorder that develops most commonly in a poverty and vulnerability scenery, where the individual and familiar necessities concerning the childhood depression are not always taken in consideration. In this context, this review demonstrates that the depression started in

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