“…Depression is associated with continued smoking following a lung cancer diagnosis [48,77], which may worsen the prognosis (e.g., through behavioral and biological pathways such as chronic hypothalamic-pituitaryadrenal axis activation) [78]. Thus, the psychological effects of having lung cancer and depression concurrently may lead to a heightened sense of vulnerability, delaying quit attempts [75]. This is of particular concern for blacks, because studies from the general population indicate that depression is more severe, chronic, debilitating, and undertreated [79] among blacks than among whites, with substantial racial disparities in the level and type of mental health care received.…”