Depressive Symptoms Underestimated in Vertiginous Patients

Ketola, Sirpa; Havia, Mari; Appelberg, Björn; Kentala, Erna

doi:10.1016/j.otohns.2007.03.037

Cited by 36 publications

(30 citation statements)

References 20 publications

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“…Using the Hospital Anxiety and Depression Scale (HADS), one study from the UK found that 17% of dizzy and vertiginous patients were depressed, and 29% were anxious 34. Another study conducted in Finland using the Beck Depression Inventory (BDI) found that 19% of patients with vertigo were depressed 35. The population-based study in Germany, discussed previously, found a 17% prevalence of self-reported depression in the past year among individuals with vestibular vertigo.…”

Section: Discussionmentioning

confidence: 93%

Vestibular vertigo and comorbid cognitive and psychiatric impairment: the 2008 National Health Interview Survey

Bigelow

Semenov

et al. 2015

J Neurol Neurosurg Psychiatry

134

105

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Our findings indicate that vestibular impairment is associated with increased risk of cognitive and psychiatric comorbidity. The vestibular system is anatomically connected with widespread regions of the cerebral cortex, hippocampus and amygdala. Loss of vestibular inputs may lead to impairment of these cognitive and affective circuits. Further longitudinal research is required to determine if these associations are causal.

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Section: Discussionmentioning

confidence: 93%

Vestibular vertigo and comorbid cognitive and psychiatric impairment: the 2008 National Health Interview Survey

Bigelow

Semenov

et al. 2015

J Neurol Neurosurg Psychiatry

134

105

View full text Add to dashboard Cite

show abstract

“…Garcia, et al [17] observed a psychological manifestation in 63.4% of vertigo patients and diagnosed as panic disorder, depressive disorder, anxiety disorder. Also Grunfeld, et al [18] and Ketola, et al [19] reported that over the 45% patients who have dizziness could be classified as depressed or anxious based on the self-reported instruments.…”

Section: Discussionmentioning

confidence: 99%

Clinical Analysis of Dizzy Patients with High Levels of Depression and Anxiety

Kim

Park

et al. 2016

J Audiol Otol

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Background and ObjectivesSome patients experiencing dizziness also report psychological distress. However, the association between vestibular deficits and psychological symptoms remains controversial. Thus, the aim of this paper is to report the proportion of patients who complained of dizziness who also had high depression and anxiety indices. Also we investigated the severity of their dizziness and the distribution of the diseases underlying this symptom.Subjects and MethodsWe assessed the dizziness and psychological distress of 544 patients experiencing dizziness using the Korean versions of the Dizziness Handicap Inventory (DHI), the Beck Depression Inventory (BDI), and the Spielberger State-Trait Anxiety Inventory (STAI). We also reviewed the audio-vestibular symtoms of patients with high levels of depression and anxiety.ResultsThe incidences of high depression and anxiety scores were 11% (60/544) and 18% (98/544), respectively. Patients with vestibular migraine were most likely to have high depression and anxiety indices. Patients in the high-BDI or high-STAI groups (117/544) obtained significantly higher DHI scores than those in neither the high-BDI nor the high-STAI group (427/544). We noticed that about 20% of the patients experiencing dizziness had high levels of psychological distress in this study; this group also suffered from various vestibular diseases and more symptoms of dizziness.ConclusionsThe results of the study suggest that psychological evaluation should be considered when assessing patients with vertigo.

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“…59 Our study documented frequent cranial nerve palsies in patients with chordoma, and the most common was diplopia. Neurological symptoms such as headache, 63 diplopia, 33 and dizziness 31,39 that are common in patients with skull base chordomas have been associated with anxiety and depression. We did not observe an association between cranial nerve deficit and depression as measured by PHQ-9 score.…”

Section: Discussionmentioning

confidence: 99%

Determinants of quality of life in patients with skull base chordoma

Diaz

Maggacis

Zhang

et al. 2014

JNS

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Object Skull base chordomas can be managed by surgical intervention and adjuvant radiotherapy. As survival for this disease increases, identification of determinants of quality of life becomes an important focus for guiding comprehensive patient care. In this study the authors sought to measure functional outcome and quality of life in patients with skull base chordomas and to identify determinants of quality of life in these patients. Methods The authors carried out an internet-based cross-sectional survey, collecting detailed data for 83 individual patients. Demographic and clinical variables were evaluated. Functional outcomes were determined by Karnofsky Performance Scale (KPS) and Glasgow Outcome Scale Extended (GOSE), quality of life was measured using the 36-Item Short Form Health Survey (SF-36), and depression was assessed using Patient Health Questions–9 (PHQ-9) instrument. Caregiver burden was assessed using the Zarit Burden Interview (ZBI). Univariate and multivariate analysis was performed to identify determinants of the physical and mental components of the SF-36. Results Patients with skull base chordomas who have undergone surgery and/or radiation treatment had a median KPS score of 90 (range 10–100, IQR 10) and a median GOSE score of 8 (range 2–8, IQR 3). The mean SF-36 Physical Component Summary score (± SD) was 43.6 ± 11.8, the mean Mental Component Summary score was 44.2 ±12.6, and both were significantly lower than norms for the general US population (p < 0.001). The median PHQ-9 score was 5 (range 0–27, IQR 8). A PHQ-9 score of 10 or greater, indicating moderate to severe depression, was observed in 29% of patients. The median ZBI score was 12 (range 0–27, IQR 11), indicating a low burden. Neurological deficit, use of pain medication, and requirement for corticosteroids were found to be associated with worse SF-36 Physical Component Summary score, while higher levels of depression (higher PHQ-9 score) correlated with worse SF-36 Mental Component Summary score. Conclusions Patients with skull base chordomas have a lower quality of life than the general US population. The most significant determinants of quality of life in the posttreatment phase in this patient population were neurological deficits (sensory deficit and bowel/bladder dysfunction), pain medication use, corticosteroid use, and levels of depression as scored by PHQ-9.

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Depressive Symptoms Underestimated in Vertiginous Patients

Abstract: Nearly 20% of vertiginous patients also have depressive symptoms. Assessment of psychiatric and psychosomatic symptoms should accompany neuro-otologic evaluation to achieve the best treatment strategy and prevent chronic outcome.

Cited by 36 publications

References 20 publications

Vestibular vertigo and comorbid cognitive and psychiatric impairment: the 2008 National Health Interview Survey

Vestibular vertigo and comorbid cognitive and psychiatric impairment: the 2008 National Health Interview Survey

Clinical Analysis of Dizzy Patients with High Levels of Depression and Anxiety

Determinants of quality of life in patients with skull base chordoma

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