Depsidones from an Endophytic Fungus Chaetomium sp. Associated with Zanthoxylum leprieurii

Abstract

A new depsidone, namely chaetosidone A (1), together with six known fungal metabolites were obtained from a culture of Chaetomium sp., an endophytic fungus isolated from Zanthoxylum leprieurii leaves. The structure of the new compound 1 was elucidated using MS and NMR experiments, and by biosynthetic considerations. Chaetosidone A (1) is the missing link in the series of orsellinic acid-derived depsidones. Compound 1, corynesidone B (2) and corynether (3) displayed inhibitory effects on two Gram-positive bacteria, Bacillus subtilis and Staphylococcus aureus, at concentrations of 40 µg per paper disk and moderate toxicity towards brine shrimp larvae (Artemia salina).

The Flavonoid Compounds from Zanthoxylum leprieurii Guill. et Perr (Rutaceae) Extracts and their Antioxidant Activity against ABTS•+

“…In Cameroon, the dried fruits are traditionally used as a spice in soups [8]. Literature has also shown that extracts of this plant possess a potential antimicrobial [9][10][11][12][13], insecticidal [14], antiplasmodial [15], cytotoxic [16,17], anti-inflammatory [18] and antioxidant activities [18][19][20].…”

Metabolites from the Endophytic Fungus Curvularia sp. M12 Act as Motility Inhibitors against Phytophthora capsici Zoospores

“…A leaf was washed with tap water to remove dust and debris. The surface of the leaf was then sterilized as described previously . The excess NaOCl was removed by washing the leaves three times with sterilized water.…”

“…The surface of the leaf was then sterilized as described previously. 40 The excess NaOCl was removed by washing the leaves three times with sterilized water. They were then air-dried on sterile filter paper.…”

Chemical Variability of Essential Oils from Zanthoxylum leprieurii Guill. et Perr (Rutaceae) According to Plant Organs

“…In Cameroon, the dried fruits are traditionally used as a spice in soups [4]. Literature has also shown that extracts of this plant possess a potential antimicrobial [5][6][7][8][9], insecticidal [10], antiplasmodial [11], cytotoxic [12,13], antiinflammatory [14] and antioxidant activities [14][15][16].…”