Depth of brain fissures in normal fetuses by prenatal ultrasound between 19 and 30 weeks of gestation

Alonso, Ignacio; Borenstein, M.; Grant, G L; Narbona, I.; Azumendi, Guillermo

doi:10.1002/uog.7660

Cited by 56 publications

(82 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our findings show that IL increases in depth in a linear fashion throughout gestation, and the growth pattern correlates well with GA. This is in line with previously reported reference limits constructed using 2D and 3D US [1,[11][12][13]18]. SF showed a quadratic rather than a linear correlation with GA, which is not in accordance with some previous data [14,18].…”

Section: Discussionsupporting

confidence: 77%

“…This is in line with previously reported reference limits constructed using 2D and 3D US [1,[11][12][13]18]. SF showed a quadratic rather than a linear correlation with GA, which is not in accordance with some previous data [14,18]. This difference may be attributed to the different technique [18] and/or technology (2D vs. 3D approach) [14] used to take these measurements.…”

Section: Discussionsupporting

confidence: 65%

“…SF showed a quadratic rather than a linear correlation with GA, which is not in accordance with some previous data [14,18]. This difference may be attributed to the different technique [18] and/or technology (2D vs. 3D approach) [14] used to take these measurements. All these values can serve as a reference to all sonographers who evaluate the development of the fetal cortex.…”

Section: Discussioncontrasting

confidence: 48%

“…However, others [18] observed a small (and maybe not clinically relevant) gender difference in the measurements of the SF, with females having smaller measurements than males.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Nomograms of the Fetal Sylvian Fissure and Insular Lobe throughout Gestation: A Multicentric, Ultrasonographic Cross-Sectional Study

Spinelli

Sica²,

Ghezzi

et al. 2018

Fetal Diagn Ther

View full text Add to dashboard Cite

Introduction: Anomalies in cortical development are often associated with an adverse outcome, but prenatal diagnosis is often impeded by the limited knowledge about normal sulci biometries throughout fetal brain development. Our aim was to provide two-dimensional ultrasonographical (2D US) nomograms of the depth of the Sylvian fissure (SF) and insular lobe (IL), as well as of the SF ratio throughout gestation in a large number of fetuses. Materials and Methods: This was a prospective cross-sectional study of 329 normal singleton pregnancies. Measurements of the SF, IL, and SF ratio were obtained in a standard transthalamic plane of the fetal head. The SF ratio was defined as SF\SF + IL. All measurements were expressed by regression equations as a function of gestational age (GA) according to the method described by Royston and Wright. The first 38 measurements were repeated twice by 2 examiners to assess the reproducibility through the intraclass correlation coefficient (ICC). Results: A significant correlation was found between GA and SF (r = 0.79; p < 0.0001) as well as IL (r = 0.77; p < 0.0001). Similarly, the SF ratio also showed a significant correlation with GA (r = 0.39; p < 0.0001). When interobserver variability was assessed, ICC was 0.97. Conclusions: Prenatal 2D US measurements of SF and IL as well as the SF ratio may be feasible and reproducible using a standard view of the fetal head. Our nomograms may be used as a reference for assessing cortical development throughout pregnancy.

show abstract

Section: Discussionsupporting

confidence: 77%

Section: Discussionsupporting

confidence: 65%

Section: Discussioncontrasting

confidence: 48%

“…However, others [18] observed a small (and maybe not clinically relevant) gender difference in the measurements of the SF, with females having smaller measurements than males.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Nomograms of the Fetal Sylvian Fissure and Insular Lobe throughout Gestation: A Multicentric, Ultrasonographic Cross-Sectional Study

Spinelli

Sica²,

Ghezzi

et al. 2018

Fetal Diagn Ther

View full text Add to dashboard Cite

show abstract

“…Our report also includes various extracerebral fluid-to-brain ratios and basic assessment of cerebral gyrification in the Sylvian fissure [40]. Firstly, there appears to be a more rapid decrease in relative amount of extracerebral fluid in CHD fetuses; however, this effect was not statistically significant.…”

Section: Discussionmentioning

confidence: 99%

Fetuses with Isolated Congenital Heart Defects Show Normal Cerebral and Extracerebral Fluid Volume Growth: A 3D Sonographic Study in the Second and Third Trimester

et al. 2019

View full text Add to dashboard Cite

Objective: The aim of our study is to explore whether the cerebral growth is delayed in fetuses with congenital heart defects (CHD) in the second and early third trimester. Methods: A prospective cohort study was conducted in 77 CHD cases, with 75 healthy controls. 3D cerebral volume acquisition was performed sequentially. The volumes of the fetal hemicerebrum and extracerebral fluid were compared by linear regression analysis, and the Sylvian fissure was measured. Results: Between 19 and 32 weeks of gestation, 158 measurements in cases and 183 measurements in controls were performed (mean 2.2/subject). The volume growth of the hemicerebrum (R² = 0.95 vs. 0.95; p = 0.9) and the extracerebral fluid (R² = 0.84 vs. 0.82, p = 0.9) were similar. Fetuses with abnormal oxygen delivery to the brain have a slightly smaller brain at 20 weeks of gestation (p = 0.02), but this difference disappeared with advancing gestation. CHD cases demonstrated a slightly shallower Sylvian fissure (mean ratio 0.146 vs. 0.153; p = 0.004). Conclusions: Our study shows no differences in cerebral growth, studied in an unselected cohort, with successive cases of isolated CHD. Even in the severest CHD cases, cerebral size is similar in the early third trimester. The cause and meaning of a shallower Sylvian fissure is unclear; possibly, it is a marker for delayed cerebral maturation or it might be an expression of decreasing amount of extracerebral fluid.

show abstract

The parieto‐occipital groove is a fissure, not a sulcus: Relevance to prenatal ultrasonographic imaging

Sarnat,

Suchet

2023

Annals of the Child Neurology Society

View full text Add to dashboard Cite

Depth of brain fissures in normal fetuses by prenatal ultrasound between 19 and 30 weeks of gestation

Abstract: Objective To establish normal reference ranges for the depth of the insula and Sylvian (SF), parieto-occipital (POF)

Cited by 56 publications

References 21 publications

Nomograms of the Fetal Sylvian Fissure and Insular Lobe throughout Gestation: A Multicentric, Ultrasonographic Cross-Sectional Study

Nomograms of the Fetal Sylvian Fissure and Insular Lobe throughout Gestation: A Multicentric, Ultrasonographic Cross-Sectional Study

Fetuses with Isolated Congenital Heart Defects Show Normal Cerebral and Extracerebral Fluid Volume Growth: A 3D Sonographic Study in the Second and Third Trimester

The parieto‐occipital groove is a fissure, not a sulcus: Relevance to prenatal ultrasonographic imaging

Contact Info

Product

Resources

About