“…This was first suggested by Corin and Aniseaux (1894) who found disappearance of plasma fibnrnogen in phosphorus intoxication. Isaac-Krieger and Hiege (1923) found fibrinogenopenia in diffuse liver diseases, often in icterus simplex and regularly in acute yellow atrophy. The significance of these findings is, however, somewhat shaken by the findings of Jacobi (1900), who demonstrated that the blood in phosphorus intoxication has fibrinolytic properties.…”