Der Tuberkulin-Hauttest: Literatur, Richtlinie und Umsetzung in der Praxis

Pucken, Valerie-Beau; Götz, F; Mansfeld, Rolf; Moder, Siegfried; Sauter‐Louis, Carola; Straubinger, Reinhard K.; Knubben‐Schweizer, Gabriela

doi:10.15653/tpg-141145

Cited by 2 publications

(1 citation statement)

References 11 publications

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“…The wide credibility intervals for the sensitivities (19.6 to 45.6) could be explained by the small data pool of true positive animals. With regard to the estimated test characteristics of the skin tests it has to be considered that these could have been affected by the performance of the skin tests [ 56 ]. The test characteristics of the pathological examination were within both datasets 76.8% (51.6–94.4%) and 78.4% (58.6–93.7%), respectively, for the sensitivity and around 99.0% (96.8–100%) for the specificity.…”

Section: Discussionmentioning

confidence: 99%

Evaluating diagnostic tests for bovine tuberculosis in the southern part of Germany: A latent class analysis

et al. 2017

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Germany has been officially free of bovine tuberculosis since 1996. However, in the last years there has been an increase of bovine tuberculosis cases, particularly in the southern part of Germany, in the Allgäu region. As a consequence a one-time tuberculosis surveillance program was revisited with different premortal and postmortal tests. The aim of this paper was to estimate diagnostic sensitivities and specificities of the different tests used within this surveillance program. In the absence of a perfect test with 100% sensitivity and 100% specificity, thus in the absence of a gold standard, a Bayesian latent class approach with two different datasets was performed. The first dataset included 389 animals, tested with single intra-dermal comparative cervical tuberculin (SICCT) test, PCR and pathology; the second dataset contained 175 animals, tested with single intra-dermal cervical tuberculin (SICT) test, Bovigam® assay, pathology and culture. Two-way conditional dependencies were considered within the models. Additionally, inter-laboratory agreement (five officially approved laboratories) of the Bovigam® assay was assessed with Cohen's kappa test (21 blood samples). The results are given in posterior means and 95% credibility intervals. The specificities of the SICT test, SICCT test, PCR and pathology ranged between 75.8% [68.8–82.2%] and 99.0% [96.8–100%]. The Bovigam® assay stood out with a very low specificity (6.9% [3.6–11.1%]), though it had the highest sensitivity (95.7% [91.3–99.2%]). The sensitivities of the SICCT test, PCR, SICT test, pathology and culture varied from 57.8% [48.0–67.6%] to 88.9% [65.5–99.7%]. The prevalences were 19.8% [14.6–26.5%] (three-test dataset) and 7.7% [4.2–12.3%] (four-test dataset). Among all pairwise comparisons the highest agreement was 0.62 [0.15–1]). In conclusion, the specificity of the Bovigam® assay and the inter-laboratory agreement were lower than expected.

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Section: Discussionmentioning

confidence: 99%

Evaluating diagnostic tests for bovine tuberculosis in the southern part of Germany: A latent class analysis

et al. 2017

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BARF (Biologisch Artgerechte Rohfütterung) als Ernährungsform bei Hunden

Kölle¹,

Schmidt²

2015

Tierarztl Prax Ausg K

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BARF (Bone And Raw Food) is an increasing trend for feeding dogs in Germany. This article provides an overview of the history and principles of this type of feeding. Risks of feeding raw-meat diets include infections of dogs with parasites, bacteria and viruses. Some of these pathogenic organisms also have zoonotic potential. Additionally, raw-meat diets often show nutritional imbalances. Over-supplementation and deficiencies of nutrients are frequently found, especially regarding calcium, the trace elements copper, zinc and iodine, vitamins A and D and the calcium : phosphorus ratio. This malnutrition can cause clinical symptoms. Therefore, checking and optimising the diet by a specialized veterinarian is strongly recommended.

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Der Tuberkulin-Hauttest: Literatur, Richtlinie und Umsetzung in der Praxis

Cited by 2 publications

References 11 publications

Evaluating diagnostic tests for bovine tuberculosis in the southern part of Germany: A latent class analysis

Evaluating diagnostic tests for bovine tuberculosis in the southern part of Germany: A latent class analysis

BARF (Biologisch Artgerechte Rohfütterung) als Ernährungsform bei Hunden

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