2022
DOI: 10.22489/cinc.2022.293
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Derangement of Cardiovascular Regulatory Mechanisms in COVID-19 Patients in Intensive Care Unit and its Association with Mortality

Abstract: The uncontrolled hyper-inflammation in critically ill patients with COVID-19 might be associated with a dysfunction of the cardiovascular regulatory mechanisms. In order to estimate the involvement of cardiovascular control in limiting the risk of mortality in COVID-19 patients we assessed the degree of asynchrony between heart period (HP) and systolic arterial pressure (SAP) variability at rest in supine condition (REST) and during an orthostatic challenge, namely the modified head-up tilt (MHUT), in 18 COVID… Show more

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“…Cardiovascular regulatory mechanisms were probed via a validated challenge, namely the modified head-up tilt (MHUT) [30], utilized in the ICU setting to disturb homeostasis by inducing sympathetic activation in response to central hypovolemia [21]. Preliminary results were presented at the 2022 Computing in Cardiology conference [31].…”
Section: Introductionmentioning
confidence: 99%
“…Cardiovascular regulatory mechanisms were probed via a validated challenge, namely the modified head-up tilt (MHUT) [30], utilized in the ICU setting to disturb homeostasis by inducing sympathetic activation in response to central hypovolemia [21]. Preliminary results were presented at the 2022 Computing in Cardiology conference [31].…”
Section: Introductionmentioning
confidence: 99%