Abstract. We study the quasi-classical limit of a quantum system composed of finitely many non-relativistic particles coupled to a quantized field in Nelson-type models. We prove that, as the field becomes classical and the corresponding degrees of freedom are traced out, the effective Hamiltonian of the particles converges in resolvent sense to a self-adjoint Schrödinger operator with an additional potential, depending on the state of the field. Moreover, we explicitly derive the expression of such a potential for a large class of field states and show that, for certain special sequences of states, the effective potential is trapping. In addition, we prove convergence of the ground state energy of the full system to a suitable effective variational problem involving the classical state of the field.