Derivatives of perfluoroisobutyric acid

A novel and efficient synthetic route to perfluoroisobutyronitrile from perfluoroisobutyryl acid

“…So the most suitable temperature was determined to be the initial reflux temperature. 18 These properties also suggested that the storage of 2 was difficult. Therefore, a separation device was used to collect 2, which was made to drip into a methanol ammonia solution for the synthesis of 3.…”

Trifluoromethyl-containing N-acylmethylenequinone imines as novel highly electrophilic agents

“…The starting methyl 2-(4-amino-3,5-dimethylphenyl)-3,3,3-trifluoro-2-hydroxypropionate 3 was prepared by Calkylation of 2,6-dimethylaniline 2 with methyl trifluoropyruvate 1 [9]. It should be noted that ester 1 was first synthesized by Knunyants et al [10]. The ester 3 was N-acylated with pfluorobenzoyl chloride.…”

Green synthesis of methyl trifluoropyruvate catalyzed by solid acids

“…Methyl ester of 2-methoxytetrafluoropropionic acid A and MTFP were synthesized by a literature procedure [3], their 1 H and 19 F NMR spectra coincided with those described in [1]. NiSO 4 Á7H 2 O, Fe 2 (SO 4 ) 3 Á5H 2 O (Acros) and gAl 2 O 3 (Engelhardt E-800, 200 m 2 /g) were used as purchased.…”

“…As a rule, MTFP is synthesized via a two-step procedure starting from hexafluoropropylene oxide [1,3] (Scheme 1).…”