Deriving temperature and age appropriate heart rate centiles for children with acute infections

Thompson, Matthew; Harnden, Anthony; Perera, Rafael; Mayon-White, Richard; Smith, Lindsay; McLeod, Diane; Mant, David

doi:10.1136/adc.2008.145011

Cited by 52 publications

(55 citation statements)

References 17 publications

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“…The results of several recent large‐scale studies456, 457, 458, 459 examining normal heart rate and respiratory rate in children are not reflected in the threshold values for respiratory rate and heart rate.…”

Section: Introductionmentioning

confidence: 94%

“…There is no basis for requiring the inclusion of body temperature or white blood cell count.The threshold value for respiratory rate overlaps with the normal range.The results of several recent large‐scale studies456, 457, 458, 459 examining normal heart rate and respiratory rate in children are not reflected in the threshold values for respiratory rate and heart rate. …”

Section: Introductionmentioning

confidence: 99%

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The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG2016)

Nishida

Ogura

Egi

et al. 2018

Acute Medicine & Surgery

157

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Background and PurposeThe Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG 2016), a Japanese‐specific set of clinical practice guidelines for sepsis and septic shock created jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in February 2017 in Japanese. An English‐language version of these guidelines was created based on the contents of the original Japanese‐language version.MethodsMembers of the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine were selected and organized into 19 committee members and 52 working group members. The guidelines were prepared in accordance with the Medical Information Network Distribution Service (Minds) creation procedures. The Academic Guidelines Promotion Team was organized to oversee and provide academic support to the respective activities allocated to each Guideline Creation Team. To improve quality assurance and workflow transparency, a mutual peer review system was established, and discussions within each team were open to the public. Public comments were collected once after the initial formulation of a clinical question (CQ), and twice during the review of the final draft. Recommendations were determined to have been adopted after obtaining support from a two‐thirds (>66.6%) majority vote of each of the 19 committee members.ResultsA total of 87 CQs were selected among 19 clinical areas, including pediatric topics and several other important areas not covered in the first edition of the Japanese guidelines (J‐SSCG 2012). The approval rate obtained through committee voting, in addition to ratings of the strengths of the recommendation and its supporting evidence were also added to each recommendation statement. We conducted meta‐analyses for 29 CQs. Thirty seven CQs contained recommendations in the form of an expert consensus due to insufficient evidence. No recommendations were provided for 5 CQs.ConclusionsBased on the evidence gathered, we were able to formulate Japanese‐specific clinical practice guidelines that are tailored to the Japanese context in a highly transparent manner. These guidelines can easily be used not only by specialists, but also by non‐specialists, general clinicians, nurses, pharmacists, clinical engineers, and other healthcare professionals.

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Section: Introductionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG2016)

Nishida

Ogura

Egi

et al. 2018

Acute Medicine & Surgery

157

View full text Add to dashboard Cite

show abstract

“…13 We also compared the 95th percentiles for our reference with the Davies ED reference at 39.5°C for the above ages as well as at 12 and 15 years. 14 The Thompson reference did not include published values for the 95th percentile, and the Davies reference did not include the 90th percentile.…”

Section: Comparison With Primary Care and Ed Patientsmentioning

confidence: 99%

“…The relationship between HR and body temperature has been characterized in 2 nonhospitalized populations: pediatric primary care patients age 3 months to 10 years with suspected acute infection 13 and in 2 cohorts of children presenting to the ED. 14,15 In this study, we sought to characterize the relationship of HR and body temperature in hospitalized children, which has not been done previously.…”

mentioning

confidence: 99%

Heart Rates in Hospitalized Children by Age and Body Temperature

Daymont

Bonafide²,

Brady

2015

Pediatrics

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BACKGROUND AND OBJECTIVES: Heart rate (HR) is frequently used by clinicians in the hospital to assess a patient's severity of illness and make treatment decisions. We sought to develop percentiles that characterize the relationship of expected HR by age and body temperature in hospitalized children and to compare these percentiles with published references in both primary care and emergency department (ED) settings.

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“…Paracetamol resets this central 'set-point': this opposes heat-conserving vasoconstriction, explaining a fall in both 4 SVR and blood pressure. However the haemodynamic impact of paracetamol may be complex given that heart rate also increases with temperature 10 .…”

Section: Introductionmentioning

confidence: 99%

Haemodynamic changes with paracetamol in critically-ill children

Ray

Brick

Raman

et al. 2017

Journal of Critical Care

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Purpose: Paracetamol has been associated with a reduction in blood pressure, especially in febrile, critically-ill adults. We hypothesised that blood pressure would fall following administration of paracetamol in critically-ill children and this effect would be greater during fever and among children with a high body surface area to weight ratio. Methods:A 12-month prospective observational study of children (0-16 years) admitted to paediatric intensive care, who underwent pulse contour analysis and received paracetamol concurrently. Results:Mean arterial blood pressure decreased significantly by 4.7% from baseline (95% CI 1.75-8.07%) in 31 children following 148 doses of paracetamol. The nadir was 2-hours postdose. The effect was pronounced in children with fever at baseline (6.4%, 95% CI 2.8-10%), although this was not statistically significant. There was no simple relationship between this effect and body surface area to weight ratio. The association between a change in blood pressure and changes in heart rate or measured stroke volume was poor; therefore it was likely that a change in the systemic vascular resistance contributes most to this effect. Conclusion:There is a significant but modest reduction in blood pressure post-paracetamol in critically-ill children. This is likely related to a change in systemic vascular resistance.

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Deriving temperature and age appropriate heart rate centiles for children with acute infections

Cited by 52 publications

References 17 publications

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG2016)

The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2016 (J‐SSCG2016)

Heart Rates in Hospitalized Children by Age and Body Temperature

Haemodynamic changes with paracetamol in critically-ill children

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