Dermal Spindle Cell Adenolipoma

AbdullGaffar, Badr; Raman, Lakshmiah G.; Prince, Sheela

doi:10.1097/dad.0b013e31829871bd

Cited by 4 publications

(14 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the previous nine cases, the SCAL were located on the thigh (three cases), arm (three cases), head (two cases) and neck (one case). [1][2][3] To our knowledge, the present case is the first reported case of SCAL on the face. The components of the sweat gland were six apocrine and three eccrine units.…”

mentioning

confidence: 56%

“…2 SCAL consists of both mesenchymal and epithelial components. [1][2][3] Mesenchymal lesions are composed of fibromyxoid stroma and spindle cells. The epithelial component is comprised of eccrine or apocrine glands.…”

mentioning

confidence: 99%

“…The components of the sweat gland were six apocrine and three eccrine units. [1][2][3] Although the pathogenesis of SCAL is unclear, Wilk et al suggested that SCAL may be a hamartoma like most adnexal or mixed tumors. 3 In our case, the epithelial component of SCAL was the apocrine gland in the face.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Cutaneous spindle cell adenolipoma on the nose: A rare variant of lipoma

Sawamura

Kajihara

Jinnin

et al. 2017

The Journal of Dermatology

View full text Add to dashboard Cite

mentioning

confidence: 56%

mentioning

confidence: 99%

See 1 more Smart Citation

Cutaneous spindle cell adenolipoma on the nose: A rare variant of lipoma

Sawamura

Kajihara

Jinnin

et al. 2017

The Journal of Dermatology

View full text Add to dashboard Cite

“…Cutaneous spindle cell adenolipoma (SCAL) is a rare variant of adenolipoma that was recently introduced . It is composed of a glandular component comprising eccrine or apocrine glands and/or ducts embedded in a fibrous and mucinous stroma with spindle cells and variable degree of lipomatous differentiation . The pathogenesis of SCAL is a matter of debate .…”

Section: Introductionmentioning

confidence: 99%

“…It is composed of a glandular component comprising eccrine or apocrine glands and/or ducts embedded in a fibrous and mucinous stroma with spindle cells and variable degree of lipomatous differentiation . The pathogenesis of SCAL is a matter of debate . Beside its controversial histogenesis, the importance of SCAL lies in its resemblance to other benign and malignant cutaneous lesions, which may lead to unnecessary immunohistochemical workup if not readily recognized.…”

Section: Introductionmentioning

confidence: 99%

Cutaneous spindle cell adenolipoma with eccrine and apocrine differentiation

Farah

Chung

2019

J Cutan Pathol

View full text Add to dashboard Cite

Cutaneous spindle cell adenolipoma (SCAL) is a recently described rare variant of lipoma with 11 cases reported to date. Here we report a consultation case of a 77-year-old male who presented with a nodule on the right nasolabial fold, diagnosed as apocrine fibroadenoma or sebaceous hyperplasia by an outside pathologist. The specimen revealed an ill-defined dermal tumor composed of mature adipocytes, bland spindle cells, ropey collagen, and dilated eccrine and apocrine glands and ducts in a fibromyxoid stroma. The spindle cells were positive for CD34 and negative for S100 protein and SOX10. These findings are consistent with those of cutaneous SCAL. The pathogenesis of this entity is controversial and includes a hamartomatous process, derivation from adipose tissue surrounding eccrine glands, or preexisting glands entrapment within a growing lipoma. In the present case, the glandular component is extensive and includes both eccrine and apocrine differentiation, which has not been previously described and further supports the hamartomatous nature.Awareness of this rare entity is helpful to prevent confusion with other look-alike primary and metastatic cutaneous lesions. K E Y W O R D Sadenolipoma, apocrine, eccrine, spindle cell lipoma

show abstract