Dermatitis alérgica de contacto por cosméticos

Laguna, C.; Cuadra, J. de la; Martín-González, B.; Zaragoza, V.; Martínez-Casimiro, L.; Alegre, V.

doi:10.1016/s0001-7310(09)70057-2

Cited by 47 publications

(9 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Bronopol caused contact sensitization in one of 202 patients with cosmetic dermatitis in another series [33]. The only patients who had positive reaction to bronopol in our series also had positive reaction from her foundation lotion.…”

Section: Discussionmentioning

confidence: 67%

Cosmetic Contact Sensitivity in Patients with Melasma: Results of a Pilot Study

Prabha¹,

Mahajan²,

Mehta³

et al. 2014

Dermatology Research and Practice

View full text Add to dashboard Cite

Background. Some of the patients with melasma perhaps have pigmented cosmetic dermatitis. However, cosmetic contact sensitivity in melasma remains poorly studied particularly in the Indian context. Objectives. To study cosmetic contact sensitivity in patients with melasma. Materials and Methods. 67 (F : M = 55 : 12) consecutive patients with melasma between 19 and 49 years of age were patch tested sequentially during January–December, 2012, with Indian Cosmetic and Fragrance Series, Indian Sunscreen Series, p-phenylenediamine, and patient's own cosmetic products. Results. 52 (78%) patients were in the age group of 20–40 years. The duration of melasma varied from 1 month to 20 years. Centrofacial, malar, and mandibular patterns were observed in 48 (72%), 18 (27%), and 1 (1%) patients, respectively. Indian Cosmetics and Fragrance Series elicited positive reactions in 29 (43.3%) patients. Cetrimide was the most common contact sensitizers eliciting positivity in 15 (52%) patients, followed by gallate mix in 9 (31%) patients and thiomersal in 7 (24%) patients. Only 2 of the 42 patients showed positive reaction from their own cosmetics while the other 5 patients had irritant reaction. Indian Sunscreen Series did not elicit any positive reaction. Conclusion. Cosmetics contact sensitivity appears as an important cause of melasma not associated with pregnancy, lactation, or hormone therapy.

show abstract

Section: Discussionmentioning

confidence: 67%

Cosmetic Contact Sensitivity in Patients with Melasma: Results of a Pilot Study

Prabha¹,

Mahajan²,

Mehta³

et al. 2014

Dermatology Research and Practice

View full text Add to dashboard Cite

show abstract

“…Fragrances and preservatives used in cosmetics are among the most common allergens in contact dermatitis [3–6]; however, recent reports from Turkey indicated a relatively low sensitization rate [7]. Concentration of the same preservative in similar products varies greatly, and excessive preservation of cosmetics potentially can lead to increased incidences of contact allergy, depending on the allergic potential of the preservative or interaction with other ingredients.…”

Section: Introductionmentioning

confidence: 99%

“…Fragrances and preservatives used in cosmetics are among the most common allergens in contact dermatitis [3][4][5][6]; however, recent reports from Turkey indicated a relatively low sensitization rate [7].Concentration of the same preservative in similar products varies greatly, and excessive preservation of cosmetics potentially can lead to increased incidences of contact allergy, depending on the allergic potential of the preservative or interaction with other ingredients. Some preservatives such as parabens are reported to cause other adverse effects, environmental pollution, carcinogenicity and hormonal disturbances or changes, but these effects vary with the preservative substance [8,9].…”

Section: Introductionmentioning

confidence: 99%

In vitro induction of apoptosis, necrosis and genotoxicity by cosmetic preservatives: application of flow cytometry as a complementary analysis by NRU

Carvalho¹,

Menezes²,

Letenski³

et al. 2011

Intern J of Cosmetic Sci

View full text Add to dashboard Cite

Preservatives are used in cosmetics to prevent microbial contamination; however, some preservatives are not free of allergenic and cytotoxic potential. Allergenicity and cytotoxicity potential values are major aspects of preservative safety, which determine limitations and maximum concentration dose in a cosmetic product. The purpose of this study was to investigate and compare the in vitro apoptosis, necrosis and genotoxicity-inducing potential of five different types of preservatives: Phenoxyethanol (PE), Propylparaben (PP), Methylparaben (MP), Benzyl Alcohol (BA) and Ethylhexyl Glycerine (EG). In vitro experiments were carried out on human dermal fibroblasts by a quantitative flow cytometry method, using specific cell markers (Annexin V, Propidium Iodide and H2AX). We compared the resulting cell viability by means of neutral red uptake (NRU) and established the IC(50) . Our results showed that PE, PP, MP and BA have similar cytotoxic mechanisms (high apoptosis and necrosis levels only at the test concentration of 1%), whereas EG showed only an apoptosis pathway. For genotoxicity, both parabens yielded the highest values. Results obtained by flow cytometry for necrosis were comparable to those produced by NRU; however, NRU does not distinguish apoptosis from necrosis. We propose that flow cytometry is a more sophisticated methodology for understanding the cytotoxic mechanisms of cosmetic preservatives and can be used to complement the NRU.

show abstract

“…Published reports list UV filters as the most frequent cause of photoallergy in cosmetics. 7 Increased awareness of their use has led to a growth in the prevalence of allergic contact dermatitis and PACD on behalf of solar filters. Organic solar filters are the most allergenic, from which the para-aminobenzoic acid (PABA) had been classically in the past the main responsible.…”

Section: Discussionmentioning

confidence: 99%

Standard photopatch test battery? Proposal based on current epidemiology and experience in our Skin Allergy Unit

Castro¹,

Velasco‐Tirado²,

Alonso‐Sardón

et al. 2021

Photoderm Photoimm Photomed

View full text Add to dashboard Cite

Photoallergic contact dermatitis (PACD) occurs after topical application of a photosensitizing substance. It is a type IV hypersensitivity reaction in which a chromophore absorbs radiation, mainly from the ultraviolet A (UVA) spectrum, and is transformed into a photoallergen in the skin. Parallel to non-photoinduced allergic contact dermatitis, patients must be previously (photo) sensitized. Due to the necessary involvement of sunlight in provoking the skin lesions, they do not typically appear in areas that are anatomically protected from the sun, for example, upper eyelids and retroauricular folds.Involvement of the rest of the face and neck should raise suspicion on PACD. 1 Diagnosis is confirmed by photopatch testing (PPT), which consists of applying allergens to be studied in duplicate and exposing only half of them to broad-spectrum UVA radiation (320-400 nm) at a dose of 5 J/cm 2 after the first 24-48 hours [day (D)1 or D2] of occlusion (eg, coinciding with the first reading). Final reading usually takes place on D4 (96 hours). 2 In Spain, the latest recommendation of an standard PPT battery (1995) included 16 allergens. 3 According to European guidelines, proposals of modifications have been made at a national level.Nevertheless, we still lack a more recent, formal, and standardized PPT recommendation. Therefore, the decision on which allergens to test is often guided by clinicians suspicion and the dermatologist's experience in this field. 3

show abstract

Dermatitis alérgica de contacto por cosméticos

Cited by 47 publications

References 21 publications

Cosmetic Contact Sensitivity in Patients with Melasma: Results of a Pilot Study

Cosmetic Contact Sensitivity in Patients with Melasma: Results of a Pilot Study

In vitro induction of apoptosis, necrosis and genotoxicity by cosmetic preservatives: application of flow cytometry as a complementary analysis by NRU

Standard photopatch test battery? Proposal based on current epidemiology and experience in our Skin Allergy Unit

Contact Info

Product

Resources

About