Dermatofibrosarcoma protuberans: Recurrence is related to the adequacy of surgical margins

Heuvel, S. Ten; Suurmeijer, Albert; Pras, Elisabeth; Ginkel, Robert J. van; Hoekstra, Harm

doi:10.1016/j.ejso.2009.07.006

Cited by 58 publications

(55 citation statements)

References 34 publications

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“…Recurrence rates have been reported to be in the range of 20% to 50%, with the majority of recurrences occurring within the first 3 years after excision (3,16,21), although late relapses may occur (33). The adequacy of surgical excision remains central to minimizing disease recurrence.…”

Section: Discussionmentioning

confidence: 98%

Pediatric Dermatofibrosarcoma Protuberans in Madrid, Spain: Multi‐institutional Outcomes

Valdivielso-Ramos

Torrelo

Campos‐Domínguez

et al. 2014

Pediatric Dermatology

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Little is known about the incidence and management of dermatofibrosarcoma protuberans (DFSP) in children. We conducted a retrospective review of all patients younger than 18 years of age treated for DFSP over a period of 11 years (2000-2011) in Madrid, Spain. The sample consisted of 13 children. The average annual incidence of DFSP in the pediatric population corresponded to 1.02 cases per million person-years (95% confidence interval 0.55, 1.73). Sites of involvement were diverse, with 15.3% of tumors found in acral locations. The median tumor size was 3.5 cm × 3 cm and the median time from apparent onset to diagnosis was 36 months. Histopathologic examination revealed conventional (77.0%), pigmented (15.4%), and myxoid (7.6%) variants. The mitotic index was consistently <5 per 10 high-power fields. All lesions were removed using surgical excision. One patient developed a local recurrence because of initial affected margins; none developed metastases. The median duration of clinical follow-up was 70.5 months. This study estimated the average annual incidence rate of DFSP in a population of patients younger than 18 years and reviewed the experience of several hospitals in the management of this tumor.

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Section: Discussionmentioning

confidence: 98%

Pediatric Dermatofibrosarcoma Protuberans in Madrid, Spain: Multi‐institutional Outcomes

Valdivielso-Ramos

Torrelo

Campos‐Domínguez

et al. 2014

Pediatric Dermatology

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“…Debido a su patrón de crecimiento infiltrante, el DFP, por lo general, se extiende más allá de los márgenes; esto explica en parte la alta tasa de recurrencia después de la resección quirúrgica convencional 12 .…”

Section: Dermatofibrosarcoma Protuberansunclassified

“…La radioterapia puede recomendarse si los márgenes de resección son positivos y la cirugía amplia de rescate no puede realizarse porque solo daría lugar a déficits estéticos o funcionales considerables 12 .…”

Section: Dermatofibrosarcoma Protuberansunclassified

Tratamiento quirúrgico de los tumores de la pared abdominal

Campos

Llombart

Estevan

et al. 2015

Revista Hispanoamericana de Hernia

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“…Hence, a wide excision of 2 to 3 cm or more of the margins beyond the clinically identifiable tumor border, down to and including the fascia, is recommended for the treatment of DFSP. [9][10][11] Currently, chemotherapy is rarely used in the treatment of DFSP. Limited case reports have not shown any significant value of conventional chemotherapy in the treatment of this neoplasm.…”

Section: Journal Of Diagnostic Medical Sonography 27(5)mentioning

confidence: 99%

Sonographic Demonstration of Dermatofibrosarcoma Protuberans

Hill

2011

Journal of Diagnostic Medical Sonography

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This case study presents the sonographic features of recurrent dermatofibrosarcoma protuberans, an uncommon soft tissue neoplasm. The original primary tumor presented five years earlier and was surgically excised. The current presentation demonstrates sonographic evaluation of several superficial left lower quadrant masses suspicious for tumor recurrence. This was confirmed by core needle biopsy and was followed by wide surgical excision. No evidence of metastasis was found, and no chemo or radiotherapy was offered.

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Dermatofibrosarcoma protuberans: Recurrence is related to the adequacy of surgical margins

Cited by 58 publications

References 34 publications

Pediatric Dermatofibrosarcoma Protuberans in Madrid, Spain: Multi‐institutional Outcomes

Pediatric Dermatofibrosarcoma Protuberans in Madrid, Spain: Multi‐institutional Outcomes

Tratamiento quirúrgico de los tumores de la pared abdominal

Sonographic Demonstration of Dermatofibrosarcoma Protuberans

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