Dermatoglyphs in patients with psoriasis

Mutations inSMARCAD1cause autosomal dominant adermatoglyphia and perturb the expression of epidermal differentiation-associated genes

“…b). Pathway analysis assigned all eight genes to three functional classes of direct relevance to ADG: epidermal growth factor receptor (EGFR) regulation, keratinocyte proliferation and differentiation, and psoriasis, a condition recently found to be associated with abnormal dermatoglyphs (Fig. c).…”