Dermatologic Manifestations of Complementary Therapy

Witkowski, Joseph A.; Parish, Lawrence Charles

doi:10.1111/j.1540-9740.2003.02166.x

Cited by 7 publications

(4 citation statements)

References 72 publications

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“…In many of the cases, these medicines contain arsenic or steroid/steroid-like substances which can lead to severe allergic reactions including SCAR. [ 16 ] CAM preparations often operate in grey market and have very little detail of components. Further even less is available in public domains.…”

Section: “Skin Is Like An Ocean's Surface Which Tells Deep Stories If...mentioning

confidence: 99%

Severe Cutaneous Adverse Reaction (SCAR): Clinical pharmacologists' viewpoint

Shafiq

Bhattacharjee

Malhotra

2022

Indian Dermatol Online J

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Section: “Skin Is Like An Ocean's Surface Which Tells Deep Stories If...mentioning

confidence: 99%

Severe Cutaneous Adverse Reaction (SCAR): Clinical pharmacologists' viewpoint

Shafiq

Bhattacharjee

Malhotra

2022

Indian Dermatol Online J

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“…Diindolylmethane, sometimes used in acne supplements, has been associated with the severe systemic allergic reaction DRESS (drug reaction with eosinophilia and systemic symptoms) [48]. Cutaneous drug reactions and urticaria have been described in herbs used to treat skin conditions [49,50].…”

Section: Allergiesmentioning

confidence: 99%

Risks of Skin, Hair, and Nail Supplements

Burns

Perez-Sanchez

Katta

2020

Dermatol Pract Concept

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Skin, hair, and nail supplements, sometimes referred to as “beauty supplements” or “ingestible skin care”, are a large and growing industry. These products may contain vitamins and minerals, sometimes in very high doses. They may also contain herbs, hormones, microbes, or animal derivatives such as fish oils and collagen powders. Dietary supplements are regulated as foods, not drugs, by the U.S. Food and Drug Administration. Therefore, manufacturers do not need to provide any proof of safety, efficacy, or quality prior to sale. This is of serious concern, as many adverse effects due to supplement components have been reported. The potential risks cover multiple categories. These include acute toxicities such as choking, as well as chronic toxicities, such as increased risk of diabetes. Teratogenicity and interaction with drugs and laboratory testing have been documented in research studies. Other risks include potentially increased risk of cancer with long-term use, allergic reactions, and others. It is vital that physicians educate their patients on these risks. As no post-marketing surveillance programs are required for supplements, our understanding of supplement risks is incomplete. Physicians should be wary of these risks and encourage further research and regulation.

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“…Modern polypharmacy means that reactions are not limited to identification of individual drugs; they also may extend to drug combinations. The proliferation of alternative medicine, which patients may not identify as a “medicine,” only compounds potential sources of allergy 12 . At the same time, matters of legal liability may encourage physicians to accept claims of allergic reaction without further inquiry 13 …”

Section: Amplificationmentioning

confidence: 99%