Dermatological Manifestations of COVID-19 in Patients Reporting to a Tertiary Care Hospital in Rawalpindi, Pakistan

Muhammad, Anjum; Iftikhar, Nadia; Mashhood, Asher Ahmed; Virdi, Gurnam; Din, Hafeez Ud; Akbar, Ali; Ahmad, Bilal; Khalid, Abrar

doi:10.7759/cureus.18973

Cited by 3 publications

(2 citation statements)

References 28 publications

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“…COVID‐19‐related cutaneous manifestations at the onset may have a significant prognostic value because they may correlate with COVID‐19 severity and mortality. According to one study, vesicular bullous lesions can appear early or late in the COVID‐19 course 88 . Similarly, acute urticaria was observed in COVID‐19 patients early in the disease course, mostly in young adults with mild to moderate infection and no associated angioedema; similar findings have been reported in the literature 58,89,90 .…”

Section: Prognostic Value Of Covid‐19 Cutaneous Manifestationssupporting

confidence: 58%

Epidemiology, clinical profiles, and prognostic value of COVID‐19‐related cutaneous manifestations in African populations: a rapid narrative review

Nyasulu,

Tamuzi

2023

Int J Dermatology

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BackgroundSkin manifestations’ true prognostic value, and clinical and epidemiological pictures in SARS‐CoV‐2 infection in African populations are poorly described and understudied. More familiarity with COVID‐19 cutaneous manifestations may aid in early clinical diagnosis or guide prognosis.MethodsIn this literature review, we looked for potential studies published from December 2019 to March 2023 on COVID‐19 cutaneous lesions in African populations. Our key questions were focused on the prognostic values of cutaneous manifestations related to COVID‐19.ResultsOur findings show that cutaneous manifestations of COVID‐19 vary by country and severity of COVID‐19, primarily multisystem inflammatory syndrome (MIS). Significant differences were also found between various dermatological lesions, primarily MIS, erythema multiforme‐like, livedoid, vesicular, or varicella‐like rashes, urticarial, maculopapular or morbilliform rashes, and chilblain‐like or pernio‐like rashes. There were 47.5% (115/242) of MIS cases reported in nine published African studies. Our findings also revealed that MIS may be diagnosed in 2–7 days due to early onset rash. Advanced age, obesity, diabetes, cardiovascular disease, HIV, tuberculosis, asthma, atopic disease, underweight, malnutrition, and malignancy were found to be associated with COVID‐19 cutaneous manifestations in African populations.ConclusionsCOVID‐19‐related skin manifestations in African populations are important as a driving force in COVID‐19 prognosis.

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Section: Prognostic Value Of Covid‐19 Cutaneous Manifestationssupporting

confidence: 58%

Epidemiology, clinical profiles, and prognostic value of COVID‐19‐related cutaneous manifestations in African populations: a rapid narrative review

Nyasulu,

Tamuzi

2023

Int J Dermatology

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“… 6 According to Muhammad et al, an association between old age and more frequent occurrence of ecchymosis, maculopapular exanthem and vesiculo-bullous rash was observed. 15 …”

Section: Discussionmentioning

confidence: 99%

Cutaneous Eruptions in the Course of COVID-19 Among Geriatric Patients in a Nursing Home in Poland

Rybak-d'Obyrn¹,

Placek²,

Owczarczyk‐Saczonek³

et al. 2022

CCID

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Purpose The aim of this study was to assess the incidence and characteristics of COVID-19 cutaneous manifestations among geriatric patients infected with the SARS-CoV-2 virus. Patients and Methods Sixty-four nursing home residents in Dobre Miasto, Poland (mean age: 79 years) infected with SARS-CoV-2 were monitored for skin lesions during the epidemic outbreak in 2020. Only five of them presented COVID-19 dermatological manifestation: vesicular (4 cases) and erythematous (1 case) skin lesions, which appeared after the remaining symptoms of the disease had resolved. Results The average time between COVID-19 onset and cutaneous manifestation was 22 days. Skin lesions persisted in five cases 112, 17, 21,19 and 27 days, respectively, and were often accompanied by pruritus and neuropathic pain. Conclusion Skin manifestations of SARS-CoV-2 infection might be misdiagnosed or overlooked, particularly among elderly patients with chronic diseases. The recognition of skin lesions due to COVID-19 might improve patients’ quality of life by reducing the intensity of symptoms such as pruritus or neuropathic pain.

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New-Onset Henoch–Schonlein Purpura after COVID-19 Infection: A Case Report and Review of the Literature

Asiri

Alzahrani

Al-Shehri

et al. 2022

Case Reports in Pediatrics

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Extrapulmonary manifestations of COVID-19 infection include a wide spectrum of cutaneous, endocrine, and cardiovascular complications. We report three cases of new-onset Henoch–Schonlein purpura (HSP) in COVID-19 infected children that were diagnosed and treated in Abha Maternity and Children Hospital, Saudi Arabia, between 28th July 2020 and 10th August 2020. All three cases were males younger than 5 years of age that presented with Henoch–Schonlein purpura characteristic rash and arthralgia without a recent history of any infection, especially respiratory infections. They all tested positive for COVID-19. At the time of the admission, pediatric COVID-19 cases were managed conservatively and we ruled out any other diagnosis before establishing the diagnosis of Henoch–Schonlein purpura according to the clinical picture. The three boys responded significantly to prednisolone and achieved a rapid recovery. We present the clinical scenario and laboratory tests of these children along with pictures of the lesions detected in each case.

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Dermatological Manifestations of COVID-19 in Patients Reporting to a Tertiary Care Hospital in Rawalpindi, Pakistan

Cited by 3 publications

References 28 publications

Epidemiology, clinical profiles, and prognostic value of COVID‐19‐related cutaneous manifestations in African populations: a rapid narrative review

Epidemiology, clinical profiles, and prognostic value of COVID‐19‐related cutaneous manifestations in African populations: a rapid narrative review

Cutaneous Eruptions in the Course of COVID-19 Among Geriatric Patients in a Nursing Home in Poland

New-Onset Henoch–Schonlein Purpura after COVID-19 Infection: A Case Report and Review of the Literature

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