Dermatological signs in liver transplant recipients

Saraç, Gülbahar; Ozcan, Kubra Nur; Başkıran, Adil; Cenk, Hülya; Saraç, Mehmet; Şener, Serpil; Yılmaz, Sezai

doi:10.1111/jocd.13944

Cited by 5 publications

(5 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Viral warts are the most common cutaneous infection in our study, which is consistent with the earlier studies. 5 , 8 , 10 The warts were predominantly found in the sun-exposed head and neck region, consistent with an earlier study performed on our renal transplant patients. 15 Viral warts, while benign, can be difficult to treat in an immunosuppressed patient.…”

Section: Discussionsupporting

confidence: 91%

“…Such an incidence rate is low and comparable with the pooled incidence rates of the studies mentioned in our review. 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 Of note is the high incidence of viral warts in our liver transplant population.…”

Section: Discussionmentioning

confidence: 93%

“…A summary of the relevant information from these articles is presented in Table V . 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 …”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Skin conditions in liver transplant recipients in a Singapore academic medical center: A retrospective cohort study

Lian

Krishnamoorthy

2021

JAAD International

View full text Add to dashboard Cite

Background Liver transplant recipients are at lifelong risk of immunosuppression-related cutaneous complications, such as malignancy and infection. Objective Our study aims to assess the epidemiology of dermatologic conditions among liver transplant recipients in an academic medical center in Singapore. Methods Medical records of liver transplant recipients on follow-up with gastroenterology and dermatology departments at the Singapore General Hospital between 2006 and 2021 were retrospectively reviewed. A literature review was subsequently performed on the keywords “liver transplant” and “dermatology.” Results A total of 99 liver transplant recipients were identified in this study. Sixty-nine patients (70%) had at least 1 dermatologic condition. Inflammatory skin conditions were the most common (53%), followed by cutaneous infection (36%) and benign cutaneous tumors (30%). Malignant and premalignant lesions were the least common skin conditions reported (10%). Our study results concurred with many other studies reported worldwide, demonstrating a low cutaneous malignancy burden after liver transplantation. Limitations The study included a small population size in a single center and did not have a pre-existing protocol for pretransplant dermatologic surveillance. Conclusion Although the incidence of skin cancer after liver transplant in Singapore is low, the patients will benefit from long-term dermatology surveillance, given the long-term risks of infection and malignant skin conditions.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 93%

See 1 more Smart Citation

Skin conditions in liver transplant recipients in a Singapore academic medical center: A retrospective cohort study

Lian

Krishnamoorthy

2021

JAAD International

View full text Add to dashboard Cite

show abstract

“…Finally, our study emphasizes the importance of dermatological follow-up for the correct diagnosis and treatment of non-oncological dermatological comorbidities among LTRs, especially infectious and drug-related dermatoses, which are notably likely to occur in this subset of patients [ 20 , 21 ].…”

Section: Discussionmentioning

confidence: 99%

De Novo Skin Neoplasms in Liver-Transplanted Patients: Single-Center Prospective Evaluation of 105 Cases

et al. 2022

View full text Add to dashboard Cite

Background and Objectives: Solid-organ transplant recipients (SOTRs) are notably considered at risk for developing cutaneous malignancies. However, most of the existing literature is focused on kidney transplant-related non-melanoma skin cancers (NMSCs). Conflicting data have been published so far on NMSC incidence among liver transplant recipients (LTRs), and whether LTRs really should be considered at lower risk remains controversial. The aim of the present study was to prospectively collect data on the incidence of cutaneous neoplasms in an LTR cohort. Materials and Methods: All LTRs transplanted at the Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit of Modena University Hospital from October 2015 to June 2021 underwent a post-transplant periodic skin check at the Dermatology Unit according to our institutional integrated care pathway. Data on the presence of cutaneous malignant and premalignant lesions were collected at every timepoint. Results: A total of 105 patients were enrolled in the present study. Nearly 15% of the patients developed cutaneous cancerous and/or precancerous lesions during the follow-up period. Almost half of the skin cancerous lesions were basal cell carcinomas. Actinic keratoses (AKs) were observed in six patients. Four patients developed in situ squamous cell carcinomas, and one patient was diagnosed with stage I malignant melanoma. Otherwise, well-established risk factors for the occurrence of skin tumors, such as skin phototype, cumulative sun exposure, and familial history of cutaneous neoplasms, seemed to have no direct impact on skin cancer occurrence in our cohort, as well as an immunosuppressive regimen and the occurrence of non-cutaneous neoplasms. Conclusions: Close dermatological follow-up is crucial for LTRs, and shared protocols of regular skin checks in this particular subset of patients are needed in transplant centers.

show abstract

“…Most of these disorders frequently appear within the first month from LT but subsequently improve. Furthermore, herpetic infections, or fungal infections (mostly tinea) of the skin and of the nail are frequently found [90].…”

Section: Dermatologic Non-oncological Complicationsmentioning

confidence: 99%

Complications in Post-Liver Transplant Patients

Agostini,

Buccianti,

Risaliti

et al. 2023

JCM

View full text Add to dashboard Cite

Liver transplantation (LT) is the treatment of choice for liver failure and selected cases of malignancies. Transplantation activity has increased over the years, and indications for LT have been widened, leading to organ shortage. To face this condition, a high selection of recipients with prioritizing systems and an enlargement of the donor pool were necessary. Several authors published their case series reporting the results obtained with the use of marginal donors, which seem to have progressively improved over the years. The introduction of in situ and ex situ machine perfusion, although still strongly debated, and better knowledge and treatment of the complications may have a role in achieving better results. With longer survival rates, a significant number of patients will suffer from long-term complications. An extensive review of the literature concerning short- and long-term outcomes is reported trying to highlight the most recent findings. The heterogeneity of the behaviors within the different centers is evident, leading to a difficult comparison of the results and making explicit the need to obtain more consent from experts.

show abstract

Dermatological signs in liver transplant recipients

Cited by 5 publications

References 12 publications

Skin conditions in liver transplant recipients in a Singapore academic medical center: A retrospective cohort study

Skin conditions in liver transplant recipients in a Singapore academic medical center: A retrospective cohort study

De Novo Skin Neoplasms in Liver-Transplanted Patients: Single-Center Prospective Evaluation of 105 Cases

Complications in Post-Liver Transplant Patients

Contact Info

Product

Resources

About