Dermatology life quality index scores in children with vitiligo: comparison with atopic dermatitis and healthy control subjects

Dertlioğlu, Selma Bakar; Çiçek, Demet; Balcı, Didem Didar; Halisdemir, Nurhan

doi:10.1111/j.1365-4632.2012.05616.x

Cited by 30 publications

(30 citation statements)

References 12 publications

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“…Total CDLQI scores were categorized as no or small (0–5), moderate , and very or extremely large (>10) QOL effect [as previously reported ], owing to a highly skewed distribution of results. Ordinal logistic regression models were constructed to examine the effect of vitiligo extent on QOL, with categorized CDLQI and individual aspects of the CDLQI divided into four responses (not at all, only a little, quite a lot, very much) as the dependent variables.…”

Section: Methodsmentioning

confidence: 99%

Quality of Life Impairment in Children and Adolescents with Vitiligo

Silverberg

2013

Pediatric Dermatology

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Vitiligo significantly affects quality of life (QOL) in adults, but little is known about the effect on QOL of pediatric vitiligo and whether the extent, distribution, and duration of vitiligo are associated with QOL. We performed an online parental questionnaire-based study (N = 350) regarding children ages 0 to 17 years with vitiligo, including validated questions about body surface area (BSA), distribution, and age of onset of vitiligo, associated symptoms, and QOL using the Children's Dermatology Life Quality Index (CDLQI). Vitiligo negatively affected numerous aspects of and total CDLQI score (median 3.0, interquartile range 5.0). Their vitiligo lesions did not bother only 4.1% of teenagers ages 15 to 17 years, versus 45.6% of children ages 0 to 6 years and 50.0% of those ages 7 to 14 years (p < 0.001). There was no association between the child's age and whether the child's vitiligo bothered the parents (p = 0.27). The most bothersome sites of vitiligo lesions for children and parents were the face (25.6% and 37.4%, respectively) and legs (26.2% and 26.2%, respectively). Eighty-two patients (30.1%) reported itching and painful skin within the past week. Using multivariate ordinal logistic regression models, it was found that an affected BSA of more than 25% was associated with self-consciousness, difficulty with friendships and schoolwork, and teasing and bullying. Lesions on the face and arms were associated with teasing and bullying. The extent of vitiligo is associated with QOL impairment in children and adolescents, especially self-consciousness, but also bullying and teasing. Different distributions of vitiligo lesions are associated with different aspects of QOL impairment. Teenagers ages 15 to 17 years seem to experience the most self-consciousness of all pediatric age groups.

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Section: Methodsmentioning

confidence: 99%

Quality of Life Impairment in Children and Adolescents with Vitiligo

Silverberg

2013

Pediatric Dermatology

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“…Almost 90% of patients have been asked questions about their white spots by strangers (25), 66% described staring at them (18), almost 50% experienced rude remarks (25,26) and 8-13% reported discrimination at work (18,27). Importantly, the knowledge about children's life with this disease has greatly improved (28)(29)(30)(31)(32). Recently our own data showed that stigmatisation was highly significant on well-being of youngsters, often leading to an impaired QoL, avoidance of situations or concealing of the white spots (33).…”

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confidence: 96%

Stigmatisation, Avoidance Behaviour and Difficulties in Coping are Common Among Adult Patients with Vitiligo

Krüger¹,

Schallreuter²

2015

Acta Derm Venerol

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Vitiligo is a non-contagious skin disorder with loss of pigmentation, often impairing patients' well-being. This study used Dermatology Life Quality Index (DLQI), Adjustment to Chronic Skin Disorders Questionnaire (ACS), Beck Depression Inventory (BDI) and additional questions to explore quality of life (QoL), coping, depression and stigmatisation and included 96 patients with vitiligo and 23 controls. Stigmatisation was common: 87/96 patients (90%) reported questions/approaches, 23/96 (24%) experienced nasty comments. Sixty-four out of 96 (66.7%) had avoided situations because of vitiligo or concealed their white spots. Sixty patients (62.5%) implied psychological stress as influential on disease's course. Patients scored higher in all questionnaires than controls (DLQI = 4.9/1.6, ACS-social anxiety/avoidance = 36.9/22.1, ACS-helplessness = 27.3/16.0, ACS-anxious-depressive mood = 19.4/15.6), except BDI (6.8/7.3). QoL of 65 patients (67.7%) was hardly impaired, 70 (72.9%) were not depressed. Treatment with pro-pseudocatalase PC-KUS reduced social anxiety/avoidance, anxious-depressive mood and depression. Patients without low-key stigmatisation scored highest in DLQI and social anxiety/avoidance. Avoidance and concealing behavior correlated with all questionnaires' scores.

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“…A limited number of studies exist in the literature that aims to evaluate emotional burden caused by vitiligo and the effect of the illness on psychosocial development, specifically in children and adolescents [25]. As there is one study that reported worse quality of life among children with vitiligo, compared to those with atopic dermatitis [26], Bilgic et al [27] have also reported that for prepubertal children, severity of vitiligo correlated with severity of depression, while in adolescents, lower levels of life quality have been reported especially if the lesions were located in body parts that were visible to others. In cases with lesions located in visible body regions, it has been reported that stigma related to the disorder might pose an increased risk for developing a psychiatric illness or a disorder, along with lower levels of quality of life, assessed [7,14,28].…”

Section: Introductionmentioning

confidence: 99%