Dermatomyositis: A Rare but Deadly Cause of Dysphagia

Paez, Marco A.; Wolfert, Marla; Tsang, Rebecca; Kathpalia, Priya; Kadanoff, Ruth; Banerjee, Promila

doi:10.14309/00000434-201310001-00671

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“…The patient could swallow saliva at 2 months and returned to normal at 3 months. Paez et al [12] also reported that severe dysphagia occurred during the treatment of dermatomyositis with corticosteroids and methotrexate, and one patient improved after IVIG. Deepak et al [17] successfully treated a 46-year-old female patient with dysphagia by IVIG.…”

Section: Discussionmentioning

confidence: 95%

“…Dysphagia is a potentially life-threatening complication of dermatomyositis and may be present in up to 60% of cases. However, a sudden onset of dysphagia without significant exacerbation of other symptoms can make diagnosis and treatment challenging [12,13]. De et al [14] showed that in the treatment of dermatomyositis with corticosteroids and immunosuppressants, 70% of patients were prone to dysphagia, and autopsy showed that most of the causes were distal esophageal motility disorders.…”

Section: Discussionmentioning

confidence: 99%

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Two-Year Treatment Tracking of Dermatomyositis Patient Complicated With Massive Pericardial Effusion and Stubborn Dysphagia: A Case Report and Literature Review

Yang¹,

Xie²,

Zhang³

et al. 2018

J Med Cases

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Dermatomyositis is a connective tissue disease mainly involving striated muscles and skins. It is rare to complicate with massive pericardial effusions. In this article, we tracked a 2-year treatment history of a dermatomyositis patient with rare complications. In the late stage of the disease, massive pericardial effusion was combined. Complications such as dysphagia, pulmonary hypertension, Sjogren's syndrome and anticardiolipin antibody syndrome posed great challenges to treatment. Massive pericardial effusion and pulmonary failure resulted in death of the patient, and anticardiolipin antibody syndrome was also one of the possible important causes of death. Good compliance could help control the disease. Massive pericardial effusion should be punctured in time. When combined with dysphagia, adequate intravenous immune globulin (IVIG) was the key to treatment.

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Section: Discussionmentioning

confidence: 95%