Dermatomyositis and Retroperitoneal Germ Cell Cancer

Vattemi, Gaetano; Tonin, Paola; Martignoni, Giuseppe; Filosto, Massimiliano; Marchioretto, F.; Rizzuto, Nicolo’; Tomelleri, Giuliano

doi:10.1159/000052090

Cited by 4 publications

(5 citation statements)

References 4 publications

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“…The persistence of dermatomyositis while he remains in remission is a frustrating feature of our case. Previous reports have documented remission of dermatomyositis following treatment of the testicular cancer, as presumably the treatment of the cancer removed the driving stimulus for the dermatomyositis 4–9,13 . We have no explanation for this in our patient, although it has been reported for other malignancies associated with dermatomyositis.…”

Section: Discussionsupporting

confidence: 44%

“…Although dermatomyositis may appear before, during or after the malignancy, most occur before the diagnosis of testicular cancer 4,5,7,8,10,11 . We postulate that the delay in symptoms of dermatomyositis in our patient may be due to the high‐dose dexamethasone which was given as part of his anti‐emetic regime.…”

Section: Discussionmentioning

confidence: 80%

“…Numerous studies have documented an increased frequency of malignancy in patients with dermatomyositis but rarely has testicular cancer been mentioned as a cause 4–9 . In all reported cases, patients had advanced stage testicular cancer (>stage IIIB).…”

Section: Discussionmentioning

confidence: 93%

“…Testicular cancer has only been rarely associated with dermatomyositis with eight published reports worldwide 4–9 . It is an important malignancy to recognize as it is the most common malignancy in young males and is potentially curable.…”

Section: Introductionmentioning

confidence: 99%

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Early‐stage testicular cancer: A rare association with dermatomyositis

Tan

Young²,

McLaren³

et al. 2010

Aust J Dermatology

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Section: Discussionsupporting

confidence: 44%

Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 93%

Section: Introductionmentioning

confidence: 99%

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Early‐stage testicular cancer: A rare association with dermatomyositis

Tan

Young²,

McLaren³

et al. 2010

Aust J Dermatology

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“…The majority of case reports detailed malignant disease occurring with DM [24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39]. Also represented were reports regarding malignancy associated with amyopathic DM [40][41][42][43], PM [44,45], inclusion body myositis [46], and DM/inclusion body myositis overlap [47].…”

Section: Case Reportsmentioning

confidence: 99%

Malignancy in patients with inflammatory myopathy

Buchbinder

Hill

2002

Curr Rheumatol Rep

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The most recent evidence from population-based cohort studies confirms the association between malignancy and dermatomyositis and polymyositis. These studies show an even stronger association between polymyositis and malignancy than previous studies, suggesting less misclassification. This is particularly true of one study that used pathologic criteria to distinguish between myositis subtypes. Recent data also confirm that the association for dermatomyositis and polymyositis is not purely caused by diagnostic suspicion or surveillance bias. More data are still required to determine individual cancer risks, although it appears that ovarian and lung cancer are associated with dermatomyositis while lung cancer and non-Hodgkin's lymphoma are associated with polymyositis. An association between malignant disease and inclusion body myositis has also been verified for the first time. Of interest, too, is the increasing number of reports documenting cases in which the clinical course of the myositis mirrors that of the cancer, supporting the notion that in some instances, myositis is a paraneoplastic disorder.

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