Dermatopathia pigmentosa reticularis

Dermatopathia pigmentosa reticularis (DPR) is a rare disorder with characteristic triad of generalized reticulate hyperpigmentation, noncicatricial alopecia and onychodystrophy. We report the first case from Syria with classical features of the triad along with hyperhidrosis and adermatoglyphia. Based on previous studies this case is distinguished by the location of alopecia on the beard which is not reported before and distinctive histopathological features were found on the biopsy.

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Dermatopathia Pigmentosa Reticularis

Rajan

Itaiya

Sakhardande

et al. 2022

Clinical Dermatology Review

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Dermatopathia pigmentosa reticularis is a rare autosomal dominant disorder. It is an ectodermal dysplasia, characterized by a triad of generalized reticulate hyperpigmentation, noncicatricial alopecia, and onychodystrophy. The mode of inheritance is probably autosomal dominant associated with mutation in keratin 14 on chromosome 17. We report the case of a 31-year-old male presented with reticulate hyperpigmentation all over the body with diffuse noncicatricial alopecia and onychodystrophy of the finger and toe nails. He also had palmoplantar hypohydrosis and poorly developed dermatoglyphics. There were no other findings of ectodermal-derived organ involvement.

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Dermatopathia pigmentosa reticularis

Cited by 5 publications

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Dermatopathia pigmentosa reticularis: A report of a case with delayed onset alopecia and onychodystrophy

Dermatopathia pigmentosa reticularis: A report of a case with delayed onset alopecia and onychodystrophy

Dermatopathia pigmentosa reticularis with beard alopecia: first report from Syria

Dermatopathia Pigmentosa Reticularis

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