Dermatopathology in sub‐Saharan Africa: a systematic 5‐year analysis of all histopathological diagnoses from the Regional Dermatology Training Centre (<scp>RDTC</scp>) in Moshi, Tanzania

Beltraminelli, Helmut; Kiprono, Samson; Zuriel, Daniel; Swai, Britta; Giabbani, Evelyne; Grossmann, Henning; Masenga, John

doi:10.1111/jdv.12877

Cited by 10 publications

(11 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The majority of the histopathologic diagnoses were inflammatory conditions (51%), followed by tumors (38.3%) and infectious conditions (7.8%) (Tables and ). Similar data were published in other dermatopathological studies from Sub‐Saharan Africa . Clinical studies from Sub‐Saharan Africa reported higher skin infections (50–85%) suggesting that infectious skin diseases were not often biopsied.…”

Section: Discussionsupporting

confidence: 87%

The use of special stains at two dermatopathology laboratories in East Africa

2015

Self Cite

View full text Add to dashboard Cite

BackgroundHistopathology is often essential in medicine to establish an accurate diagnosis, which forms the basis of disease treatment. Pathology laboratories are scarce in most Sub-Saharan Africa (SSA) where Dermatopathology is only a developing field. In resource-poor countries, most specimens are analysed only after Haematoxylin and Eosin staining (H&E). The availability of other special stains (SS) is very limited and restricted to only few centres. The aim of this study is to analyse the extent of dermatopathological cases which can be adequately diagnosed after H&E alone. Secondly, to investigate which cases required further SS. MethodsAll skin specimens submitted to two University Hospitals (Tanzania and Kenya) were included in this study. All specimens were first analysed with H&E and a diagnosis established when possible. All cases in which an accurate diagnosis after H&E only was not possible, were registered and evaluated after further SS. ResultsA total of 386 specimens were examined. A proper histological diagnosis with H&E alone was possible in 344 (89.1%) samples. In 45 (11.6%) cases, mostly skin infections, further SS were necessary. ConclusionA proper histological diagnosis was possible after H&E alone in almost 90% of the specimens submitted to the two laboratories in SSA.

show abstract

Section: Discussionsupporting

confidence: 87%

The use of special stains at two dermatopathology laboratories in East Africa

2015

Self Cite

View full text Add to dashboard Cite

show abstract

“…Another study found that in 78% of cases, the correct diagnosis was already included in the clinician's pathology requisition form [44]. A 5-year study in Tanzania looked at the case distribution and found a similar diagnostic spectrum, with the exception of the relatively high number of Kaposi's sarcoma and leprosy cases [45]. In addition to these two diseases, a similar study in Ethiopia reported high rates of cutaneous tuberculosis and leishmaniasis [46].…”

Section: Discussionmentioning

confidence: 99%

Dermatopathological Correlation of Clinically Challenging Cutaneous Lesions: A Single Center Experience of 2184 cases

Özcan¹,

Özlü²,

Karagün³

et al. 2022

Dermatol Pract Concept

View full text Add to dashboard Cite

Introduction: Although textbooks provide the ideal clinical and histopathological findings, in practice we usually have fewer, and sometimes contradictory, findings to work with. Objectives: The primary goal of this study is to categorize the diagnoses of clinically challenging skin lesions, thereby identifying the most common diagnostic scenarios encountered by dermatopathologists in practice and the most perplexing differential diagnoses submitted by clinicians. Our secondary aim is to investigate how the case profile and clinician decision-making processes changed during the COVID-19 pandemic.Methods: We classified 2184 pathology reports into four major categories: inflammatory, neoplastic, non-diagnostic, and other. In each category, the three most frequently reported diagnoses were listed. For each listed diagnosis, the top 3 most frequently used differential diagnoses by the clinician prior to biopsy are listed. The period one year after and before the first nationally reported COVID-19 case was compared using the same classification.Results: The most common diagnoses and clinical differential diagnoses were listed for each category, with 45.4% being inflammatory and 27.4% being neoplastic diseases. Non-diagnostic reports accounted for 11.4% of all reports. The overall number of reports has decreased drastically since the pandemic, and the rates of keratinocytic and melanocytic neoplasms have increased, while the rates of other malignancies and spongiotic diseases have decreased.Conclusion: Although a trained eye can easily identify skin lesions when they are typical, even diseases we are familiar with can present atypically in real life. In these cases, histopathological examinations and clinicopathological correlation are critical in making an accurate diagnosis.

show abstract

“…Afirma, ademais, que no ocidente essa relação é inversa. Em outro estudo retrospectivo, apesar de proporção menor, mostrou maior incidência de CBC (11,12). O melanoma é o tipo menos frequente de câncer de pele e costuma ter prognóstico mais grave.…”

Section: Discussionunclassified

Tumores de pele sincrônicos em paciente albino: relato de caso / Synchronous and invasive cutaneous skin cancer in an albino patient: case report

Silva¹,

Mendes²,

Mota³

et al. 2021

Braz. J. Hea. Rev.

View full text Add to dashboard Cite

O albinismo é decorrente de uma condição hereditária de caráter autossômico recessivo, caracterizado por uma hipopigmentação geral da pele, acarretando menor proteção contra raios solares, logo estão mais sujeitos a queimaduras solares, elastose, lesões prémalignas como a ceratose actínica e cânceres de pele. O carcinoma escamocelular é o mais comum em albinos, seguido pelo basocelular. A ocorrência de tumores sincrônicos de diferentes subtipos é bastante incomum de acontecer nessa população, por isso, poucos casos são relatados na literatura. O presente relato tem como objetivo abordar um caso de tumores sincrônicos avançados em paciente albino, diagnosticado no ambulatório de oncologia da Santa Casa de Misericórdia de Maceió-AL. A metodologia foi realizada com dados de anamnese e exame físico do paciente, exames complementares e consulta a

show abstract

Dermatopathology in sub‐Saharan Africa: a systematic 5‐year analysis of all histopathological diagnoses from the Regional Dermatology Training Centre (RDTC) in Moshi, Tanzania

Cited by 10 publications

References 37 publications

The use of special stains at two dermatopathology laboratories in East Africa

The use of special stains at two dermatopathology laboratories in East Africa

Dermatopathological Correlation of Clinically Challenging Cutaneous Lesions: A Single Center Experience of 2184 cases

Tumores de pele sincrônicos em paciente albino: relato de caso / Synchronous and invasive cutaneous skin cancer in an albino patient: case report

Contact Info

Product

Resources

About