Dermite livédoïde de Nicolau sus-pubienne après injections sous-cutanées d’acétate de glatiramère

Embolia Cutis Medicamentosa after Subcutaneous Injection with Glatiramer Acetate

“…Several cases of ECM have been reported after intramuscular, subcutaneous, and even after intraarticular injection of various drugs, such as non-steroidal anti-inflammatory drugs (NSAIDs), vitamin K, vitamin B12, penicillin, antihistamines, corticosteroids, local anesthetics, vaccines, and interferon-α and -β [8,9]. There are only few descriptions of necrotic ECM after treatment with GA (20 and 40 mg/day) [7,8,[10][11][12][13][14]. In 2 of these patients, further injections of GA led to another episode of ECM after well-tolerated injections in-between [10,11].…”