Dermoscopic and Immunohistochemical Observations in Anetodermic Pilomatricoma: A Case Report

Chen, Hao-Song; Li, Fang-Gu; Huang, Wenbin; Fan, Yi‐Ming

doi:10.2340/00015555-3449

Cited by 3 publications

(5 citation statements)

References 13 publications

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“…Such lesions can be ulcerated or non-ulcerated and may exhibit variable pigmentation with combinations of blue-gray, red, and white/yellow colors [ 4 , 6 – 8 , 10 , 12 – 14 ]. Additionally, atypical pilomatricomas with an anetodermic appearance have also been reported [ 5 , 9 , 11 ]. In the literature, ultrasound was used to confirm, support or exclude the diagnosis of pilomatricoma [ 18 , 19 ].…”

Section: Discussionmentioning

confidence: 99%

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Pilomatricoma: Clinical, Dermoscopic Findings and Management in 55 Pediatric Patients and Concise Review of the Literature With Special Emphasis on Dermoscopy

Chessa,

Baracca,

Rossi

et al. 2024

Dermatology Practical &Amp; Conceptual

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Introduction: Pilomatricoma is a benign adnexal dermal or subcutaneous tumor derived from immature hair matrix cells. Objectives: The aim of our study is to evaluate clinical and dermoscopic features of pilomatricomas, with a specific focus on pediatric lesions, and to provide a concise review of the existing literature. Methods: A single-center retrospective study was undertaken on 55 patients with a histopathological diagnosis of pilomatricoma referred to the Dermatology Unit, University of Bologna, Bologna, Italy, between 2005 and 2023. Pilomatricomas were retrospectively evaluated relying on clinical and dermoscopic images. A PubMed search was conducted. All the relevant research up to July 31, 2023, was reviewed. We classified the cases as “typical” or “atypical” based on whether they were suspected of being pilomatricomas or not. Results: A total of 55 children with pilomatricomas.were observed and studied. Two patients presented with 2 pilomatricomas, leading to the identification of 58 pilomatricomas. Typical’ pilomatricomas were observed in 79% of cases as nodular and pigmented lesions with one or more colors, ranging from blue-gray to red to yellow/white, evident on clinical examination and even better on dermoscopy. In 21% of cases, pilomatricomas presented in an ‘atypical’ form, which did not allow for a well-founded suspicion, placing them in differential diagnosis with other lesions and therefore requiring histological examination. Conclusions: According to our case series and systematic review of the literature, clinical appearance and dermoscopy may be sufficient to diagnose or suspect pilomatricoma in around 80% of cases, while histological examination is necessary to confirm the diagnosis in the remaining 20% of cases.

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Section: Discussionmentioning

confidence: 99%

“…The tricolor appearance could be considered as a dermoscopic clue to make the diagnosis. In this regard, several authors reported typical pilomatricomas characterized by a bi- or tricolor nodular aspect at dermoscopy [ 3 – 6 , 9 , 10 , 13 ].…”

Section: Discussionmentioning

confidence: 99%

Pilomatricoma: Clinical, Dermoscopic Findings and Management in 55 Pediatric Patients and Concise Review of the Literature With Special Emphasis on Dermoscopy

Chessa,

Baracca,

Rossi

et al. 2024

Dermatology Practical &Amp; Conceptual

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“…Clinical types of the tumor include familial, perforating, multinodular [ 5 ], exophytic, anetodermic, and giant PM [ 6 ]. The bullous type is seen in only 3 to 6% of cases [ 7 ]. It is seen more frequently in women and children, and often occurs on the shoulders and upper arms.…”

Section: Discussionmentioning

confidence: 99%

Dermotoscope assisted diagnosis of adolescent bullous pilomatricoma: six case reports

Liu,

et al. 2024

BMC Pediatr

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Background Pilomatricoma (PM) is a cutaneous benign neoplasm derived from the hair matrix. It clinically presents as a solitary and firm nodule overlying normal epidermis and is usually not easy to be noticed at early stage. Nevertheless, when special bullous lesion occurs in a short time or even ulcerates, preoperative diagnosis by a dermatologist is often challenging especially when the pediatric patients refuse biopsy. Case presentation We present six bullous PM cases and particularly conduct correlation analysis on the dermotoscopy and histopathology detection data. The basic information, medical history, symptoms and lesion morphology results of the patients were also provided. We found that the incidence of bullous PM was higher in females than in males, and most patients were adolescents and the predilection location seem to be consistent in the vaccine injection site. The dermatoscopic features of bullous PM reported were luminous yellow structure below, with gray-blue homogeneous areas and branched capillary. The histological features were consistent with PM, and evident epidermis bullae were above the tumor with extraordinary dilation of lymphangion in the upper dermis. The patients described in this study were Chinese patients in Han population included 4 females and 2 males, coincidentally, they are almost teen-age, respectively are 5,11,17,19,21,22 year-old. Conclusions This study reported and analyzed the dermotoscopy and clinical characteristics of bullous PM, dermotoscopy may guide as a rapid and reliable technique in bullous PM diagnosis.

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“…Acanthosis and increased basal pigmentation in the overlying epidermis also contribute to the bluish rim. 5 Vascular structures (telangiectasias) and reddish homogenous areas correspond to the vascular dilation and haemorrhages, which are distinctly visible due to loss of dermal connective tissue. 6 Another distinct dermoscopic finding was the presence of shiny white streaks on polarised light, which was due to altered collagen in the underlying dermis.…”

Section: Casementioning

confidence: 99%

“…The white areas were invariably surrounded by a bluish rim, which represent the pigmentation within the tumour cells or dermal melanophages. Acanthosis and increased basal pigmentation in the overlying epidermis also contribute to the bluish rim 5 . Vascular structures (telangiectasias) and reddish homogenous areas correspond to the vascular dilation and haemorrhages, which are distinctly visible due to loss of dermal connective tissue 6 .…”

Section: Casementioning

confidence: 99%

Anetodermic pilomatricoma: A clinical, histopathological and dermoscopic perspective

et al. 2022

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Dermoscopic and Immunohistochemical Observations in Anetodermic Pilomatricoma: A Case Report

Cited by 3 publications

References 13 publications

Pilomatricoma: Clinical, Dermoscopic Findings and Management in 55 Pediatric Patients and Concise Review of the Literature With Special Emphasis on Dermoscopy

Pilomatricoma: Clinical, Dermoscopic Findings and Management in 55 Pediatric Patients and Concise Review of the Literature With Special Emphasis on Dermoscopy

Dermotoscope assisted diagnosis of adolescent bullous pilomatricoma: six case reports

Anetodermic pilomatricoma: A clinical, histopathological and dermoscopic perspective

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