Dermoscopic clues in the skin lesions of secondary syphilis

Mathur, M; Acharya, Prakash; Karki, Alina; Shah, Jyoti; Kc, Nisha

doi:10.1002/ccr3.1999

Cited by 16 publications

(15 citation statements)

References 12 publications

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“…[2][3][4] The main dermoscopic findings of secondary syphilis are Biett's collarette and yellow-orangish hue, while the vascular pattern is indefinite. [5][6][7] Typical Biett's collarette presents as a circular, thin, scaling edge progressing in an outward direction and surrounded by an erythematous halo. 5 The orangish background may originate from erythrocyte extravasation and hemosiderin deposition in the dermis.…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological, dermoscopic, and ultrastructural observation of annular secondary syphilis on the penis

Huang

Chen

et al. 2020

Int J STD AIDS

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Annular syphilis may range from mildly raised lesions with scaly borders to verrucous plaques. Localized annular syphilis on the genitalia has been rarely reported in HIV-negative cases. This paper reports a case of annular secondary syphilis on the penis. Dermoscopy showed peripheral dotted and short linear vessels and white scaling with a relatively clear central area in an erythematous annular plaque. Histopathology revealed mild hyperkeratosis, parakeratosis, psoriasiform acanthosis, and focal basal vacuolar degeneration with lichenoid, perivascular, and periadnexal infiltrate of lymphohistiocytes and plasma cells in the superficial dermis. Silver stain showed several spirochetes in the lower epidermis and superficial dermis. Electron microscopy revealed a few intercellular and intracytoplasmic spirochetes in the basal epidermis and free spirochetes in the papillary dermis. Rapid plasma reagin and Treponema pallidum particle agglutination assays were positive. The lesions disappeared after intramuscular benzathine penicillin, with no relapse at six-month follow-up.

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Section: Discussionmentioning

confidence: 99%

Clinicopathological, dermoscopic, and ultrastructural observation of annular secondary syphilis on the penis

Huang

Chen

et al. 2020

Int J STD AIDS

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“…Syphilis are bright coppery red papular lesions surrounded by a fine circular desquamation called Biett's collar, they are symmetrical and diffuse on the face, trunk and limbs. Palmoplantar localization is rare but characteristic of the disease [4]. The clinical aspect sometimes takes on other presentations that can make the diagnosis difficult.…”

Section: Sirmentioning

confidence: 99%

Progressive dermoscopy of palmoplantar syphilides

Dassouli¹,

Douhi²,

Choukri³

et al. 2022

Our Dermatol Online

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“… 37 , 38 Although it is visible to the naked eye, dermoscopy allows its detection in smaller lesions, where the collarette sign is not clinically evident. 39 They characteristically present with a diffuse orange or yellowish-red background. 37 , 38 It has been postulated that it might correspond to the extravasation of red blood cells and hemosiderin deposits that occur in secondary syphilis lesions.…”

Section: Bacterial Infectionsmentioning

confidence: 99%

Dermoscopy of skin infestations and infections (entomodermoscopy) – Part I: dermatozoonoses and bacterial infections

Bakos

Reinehr

Escobar

et al. 2021

Anais Brasileiros de Dermatologia

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Dermoscopy is an essential in vivo diagnostic technique in the clinical evaluation of skin tumors. Currently, the same can also be said about its implications when approaching different clinical situations in Dermatology. A growing number of reports on dermatological scenarios and diseases have been published, in which dermoscopy has been of great diagnostic help. The term “entomodermoscopy” was coined to describe dermoscopic findings in skin infestations and also in dermatoses of infectious etiology. In part I of this article, the main dermoscopic descriptions of zoodermatoses and bacterial infections will be addressed. In many of them, such as scabies, pediculosis, myiasis, and tungiasis, it is possible to identify the pathogen and, consequently, attain the diagnosis more quickly and use the technique to follow-up therapeutic effectiveness. In other situations that will be described, dermoscopy can allow the observation of clinical findings with greater detail, rule out differential diagnoses, and increase the level of confidence in a clinical suspicion.

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Dermoscopic clues in the skin lesions of secondary syphilis

Abstract: Key Clinical Message Secondary syphilis may have a varied clinical presentation and might pose a diagnostic difficulty when a typical history is absent. We describe the dermoscopic clues of the skin lesions at different stages of the disease which could culminate to a proper diagnosis.

Cited by 16 publications

References 12 publications

Clinicopathological, dermoscopic, and ultrastructural observation of annular secondary syphilis on the penis

Clinicopathological, dermoscopic, and ultrastructural observation of annular secondary syphilis on the penis

Progressive dermoscopy of palmoplantar syphilides

Dermoscopy of skin infestations and infections (entomodermoscopy) – Part I: dermatozoonoses and bacterial infections

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