Dermoscopic features of acral lentiginous melanoma in a large series of 110 cases in a white population

Phan, Alice; Dalle, S.; Touzet, Sandrine; Ronger-Savlé, S.; Balme, B.; Thomas, Luc

doi:10.1111/j.1365-2133.2009.09594.x

Cited by 121 publications

(135 citation statements)

References 21 publications

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“…In particular, the area, perimeter and diameters (maximum and minimum) were larger. This correlated well with reports in the literature [41,42]. Indeed, in the Saida algorithm, a diameter of PP-PSL greater or less than 7 mm is considered an important cut-off in deciding whether to follow up or remove equivocal lesions [34].…”

Section: Discussionsupporting

confidence: 74%

“…In this regard, it is worth recalling that many authors have reported a combination of many elements and disorganization in their disposition within a PSL as a dermoscopic feature peculiar to melanoma [20,21,22,23,43,44]. The shape of the edges is undoubtedly another factor that has proved crucial in the differentiation of palmoplantar nevi and palmoplantar melanomas [19,20,41,45]. In fact, the variables related to boundary evenness (variance of border gradient, border homogeneity and border interruptions) showed statistically significant differences between palmoplantar melanoma and nevi.…”

Section: Discussionmentioning

confidence: 99%

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Dermoscopy and Digital Dermoscopy Analysis of Palmoplantar ‘Equivocal’ Pigmented Skin Lesions in Caucasians

et al. 2012

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Background/Aim: The diagnosis of palmoplantar melanoma is often delayed and misdiagnosis is common, due to frequently unusual clinical presentation. We used a digital dermoscopy analyzer with a series of palmoplantar pigmented skin lesions (PP-PSL), and we compared sensitivity, specificity and diagnostic accuracy obtained with digital dermoscopy analysis (DDA) and classical dermoscopy. Methods: Digital dermoscopy images of 107 PP-PSL were retrospectively obtained from the database of images of 3 Italian centers. The lesions (25 melanomas and 82 nevi) were all removed because of the presence of clinical and/or dermoscopic suspicious features. All digital images were analyzed using appropriate algorithms, and the diagnostic accuracy of the model was calculated. For comparison, dermoscopic images were clinically evaluated by two dermatologists and the Cohen ĸ concordance with DDA was calculated. Results: The stepwise logistic regression analysis selected only 5 parameters out of 49. The logistic model achieved a sensitivity of 96% and a specificity of 87.8%. The Cohen ĸ concordance, evaluated by the Landis and Koch scale, supplied a substantial agreement between dermoscopy and DDA. Conclusions: DDA might be a useful diagnostic instrument in the evaluation of preselected PP-PSL. However, these findings should be confirmed in a formal clinical trial.

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Section: Discussionsupporting

confidence: 74%

Section: Discussionmentioning

confidence: 99%

Dermoscopy and Digital Dermoscopy Analysis of Palmoplantar ‘Equivocal’ Pigmented Skin Lesions in Caucasians

et al. 2012

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“…With 66 acral melanomas this is the largest series on dermoscopy of acral melanoma in a predominantly Caucasian population to date [13,14,15,16]. Eight lesions (3 melanomas) were from Asian patients.…”

Section: Discussionmentioning

confidence: 99%

Dermoscopy of Acral Melanoma: A Multicenter Study on Behalf of the International Dermoscopy Society

et al. 2013

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Background: Most studies on dermoscopy of acral lesions were conducted in Asian populations. In this study, we analyzed these features in a predominantly Caucasian population. Objective: Estimate the prevalence of dermoscopic features in acral lesions, and assess their level of agreement between observers. Methods: In this retrospective multicenter study, 167 acral lesions (66 melanomas) were evaluated for 13 dermoscopic patterns by 26 physicians, via a secured Internet platform. Results: Parallel furrow pattern, bizarre pattern, and diffuse pigmentation with variable shades of brown had the highest prevalence. The agreement for lesion patterns between physicians was variable. Agreement was dependent on the level of diagnostic difficulty. Conclusion: Lesions with a diameter >1 cm were more likely to be melanoma. We found as well that a benign pattern can be seen in parts of melanomas. For this reason one should evaluate an acral lesion for the presence of malignant patterns first.

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“…17,21 Acral melanomas are located on palms, soles, fingers, toes and in the nail unit. The dermoscopic features of melanomas located on the palms and soles were described Saida et al 22 The two most prevalent features were irregular diffuse pigmentation and the parallel-ridge pattern with a sweat glands infiltration. 22 Presence of the latter feature allows detection of melanoma with the diagnostic 86.4% sensitivity and 99% specificity.…”

Section: 11mentioning

confidence: 99%

“…Approximately 43% of acral melanomas show a combination of three or more types of blood vessels. 22 In the case of acral melanoma of the nail unit, the most prominent pattern is the presence of irregular lines (70%). Nail dystrophy occurs in 43% of cases.…”

Section: 11mentioning

confidence: 99%

Modern non-invasive diagnostic techniques in the detection of early cutaneous melanoma

Kardynał¹,

Olszewska

2014

J Dermatol Case Rep

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Over the past few years melanoma has grown into a disease of socio-economic importance due to the increasing incidence and persistently high mortality rates. Melanoma is a malignant tumor with a high tendency to metastasize. Therefore, an extremely important part of the therapeutic process is to identify the disease at an early stage: in situ or stage I. Many tools for early diagnosis of melanoma are available today, including dermoscopy, videodermoscopy and in vivo reflectance confocal microscopy. Other methods such as high frequency ultrasound, optical coherence tomography and electrical impedance spectroscopy may serve as additional diagnostic aids. Modern imaging techniques also allow the monitoring of melanocytic skin lesions over months or years to detect the moment of malignant transformation. This review summarizes the current knowledge about modern diagnostic techniques, which may aid early diagnosis of

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Dermoscopic features of acral lentiginous melanoma in a large series of 110 cases in a white population

Cited by 121 publications

References 21 publications

Dermoscopy and Digital Dermoscopy Analysis of Palmoplantar ‘Equivocal’ Pigmented Skin Lesions in Caucasians

Dermoscopy and Digital Dermoscopy Analysis of Palmoplantar ‘Equivocal’ Pigmented Skin Lesions in Caucasians

Dermoscopy of Acral Melanoma: A Multicenter Study on Behalf of the International Dermoscopy Society

Modern non-invasive diagnostic techniques in the detection of early cutaneous melanoma

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