Dermoscopic features of combined melanocytic nevi

Giorgi, Vincenzo De; Massi, Daniela; Salvini, Camilla; Trez, Elisa Gobbato; Mannone, Francesca; Carli, Paolo

doi:10.1111/j.0303-6987.2004.00237.x

Cited by 41 publications

(48 citation statements)

References 9 publications

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“…Scolyer, et al 32 recently underscored that a correct clinical diagnosis of combined nevus was given only in 2.4% of their cases. On the other hand, De Giorgi, et al 33 stated that dermoscopy can provide useful information for a conservative management of combined nevi, at least when a clear-cut blue nevus component is present. In the present study, combined blue nevi were often Ôbrown-blue' nevi, which were all retrospectively identifiable as benign lesions by dermoscopy.…”

Section: Discussionmentioning

confidence: 99%

The many faces of blue nevus: A clinicopathologic study

et al. 2006

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Background: In recent years, several histopathologic variants of blue nevus have been identified, whose clinical and dermoscopic correlates need further clarification. Methods: A comparative evaluation of histopathologic and dermoscopic features was carried out on 52 melanocytic proliferations belonging to the morphologic spectrum of blue nevus. Results: On dermoscopy, all lesions showed a homogeneous, structureless pigment pattern, with a curious variety of colors (blue, white-blue, black, brown, and polychromatic). Histopathologically, the majority of blue lesions were common blue nevi (11/19); the majority of white-blue lesions were Ôhypochromic' (sclerotic, hypomelanotic, and amelanotic) blue nevi (17/22); all the black lesions were Ôcompound' blue nevi (2/2); the majority of brown lesions were combined blue nevi (3/4); the unusual polychromatic dermoscopic appearance was often associated with a histopathologic diagnosis of deep penetrating nevus (2/5). Conclusion: A dermoscopic-pathologic approach now allows us to identify Ôblue' (common) blue nevi, Ôwhite' (hypochromic) blue nevi, Ôblack' (compound) blue nevi, Ôbrown' (combined) blue nevi, and Ôpolychromatic' (deep penetrating) blue nevi. A better recognition of the many dermoscopic faces of blue nevi is expected to give a morphologic guideline for the clinical management of these lesions. Ferrara G, Soyer HP, Malvehy J, Piccolo D, Puig S, Sopena J, Zalaudek I, Argenziano G. The many faces of blue nevus: A clinicopathologic study.

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Section: Discussionmentioning

confidence: 99%

The many faces of blue nevus: A clinicopathologic study

et al. 2006

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“…Colors allow estimation of the location of pigmented cells in the skin (Figure 1). [20][21][22][23][24]64 …”

Section: Colormentioning

confidence: 99%

“…[20][21][22]64 Black and brown are due to pigmentation within the epidermis and are the most common colors seen in nevi with a prevailing epidermal component. Gray and blue represent pigmentations found in the upper and middle dermis, respectively, and are often seen in nevi with dermal involvement.…”

Section: Commentmentioning

confidence: 99%

Using Dermoscopic Criteria and Patient-Related Factors for the Management of Pigmented Melanocytic Nevi

Zalaudek

Docimo

Argenziano³

2009

Arch Dermatol

101

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Objective: To review recent dermoscopy studies that provide new insights into the evolution of nevi and their patterns of pigmentation as they contribute to the diagnosis of nevi and the management of pigmented melanocytic nevi. Data Sources: Data for this article were identified by searching the English and German literature by Medline and Journals@Ovid search for the period 1950 to January 2009. Study Selection: The following relevant terms were used: dermoscopy, dermatoscopy, epiluminescence microscopy (ELM), surface microscopy, digital dermoscopy, digital dermatoscopy, digital epiluminescence microscopy, digital surface microscopy, melanocytic skin lesion, nevi, and pigmented skin lesions. There were no exclusion criteria. Data Synthesis: The dermoscopic diagnosis of nevi relies on the following 4 criteria (each of which is characterized by 4 variables): (1) color (black, brown, gray, and blue); (2) pattern (globular, reticular, starburst, and homogeneous blue pattern); (3) pigment distribution (multifocal, central, eccentric, and uniform); and (4) special sites (face, acral areas, nail, and mucosa). In addition, the following 6 factors related to the patient might influence the pattern of pigmentation of the individual nevi: age, skin type, history of melanoma, UV exposure, pregnancy, and growth dynamics. Conclusions: The 4×4×6 “rule” may help clinicians remember the basic dermoscopic criteria of nevi and the patient-related factors influencing their patterns. Dermoscopy is a useful technique for diagnosing melanocytic nevi, but the clinician should take additional factors into consideration to optimize the management of cases of pigmented lesions.

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“…When presented in combined nevi, blue coloration is usually located in the center of the lesion. Peripheral distribution can also be observed, like in our case, although it is more commonly exhibited in melanoma (7,8). Since the lesion of our patient presented in the skin area not suitable for daily skin inspection, the patient could not provide reliable information on the possible changes in the size, shape and color of the nevus, indicating the need for surgical excision and histopathological examination.…”

Section: Discussionmentioning

confidence: 61%

Dermoscopy Case of the Month Combined Nevus - a Case Report

Jović

Vidović

Popović

et al. 2017

Serbian Journal of Dermatology and Venereology

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Combined nevi are melanocytic lesions composed of two or more distinct types of melanocytic populations within the same lesion. Different types of combined nevi may form bizarrely shaped, multicolored skin lesions, making them one of the greatest melanoma mimickers. We report a 48-year-old female patient with suspicious skin lesion in the left lumbar region. Clinically, there was an oval, slightly asymmetrical lesion measuring 6 x 4 mm, showing multiple colors and shades of brown and black. A dermoscopic examination revealed a brown-bluish coloration in the right part of the lesion, while a fine pigment network with perifollicular halo was found in the left part of the lesion, suggesting the diagnosis of a combined nevus. Histological examination showed a poorly circumscribed proliferation of dendritic melanocytes in the superficial and deep dermis and proliferation of melanocytes in the dermoepidermal junction. A surgical excision of the tumor was performed, in order to confirm the dermoscopic findings. In conclusion, dermoscopy is useful in differentiating combined nevi from other melanocytic lesions.

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Dermoscopic features of combined melanocytic nevi

Cited by 41 publications

References 9 publications

The many faces of blue nevus: A clinicopathologic study

The many faces of blue nevus: A clinicopathologic study

Using Dermoscopic Criteria and Patient-Related Factors for the Management of Pigmented Melanocytic Nevi

Dermoscopy Case of the Month Combined Nevus - a Case Report

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