Dermoscopic-Histopathologic Correlation of Cutaneous Lymphangioma Circumscriptum

Cutaneous lymphangioma circumscriptum: The relevance of clinical, dermoscopic, radiological, and histological assessments

“…Dermoscopy presents a lacunar/saccular pattern, because of the presence of lymphatic fluid varying from light brown to violet color, a result of the volume of blood wrapped by pale septa, which shows the hypopyon‐like, characterized by blood sedimentation . Another dermoscopic pattern consists of colored areas varying from yellowish white to diffuse rose with linear and sharp vessels .…”

“…2,3,7,8 Dermoscopy presents a lacunar/saccular pattern, because of the presence of lymphatic fluid varying from light brown to violet color, a result of the volume of blood wrapped by pale septa, which shows the hypopyon-like, characterized by blood sedimentation. 3,8,9 Another dermoscopic pattern consists of colored areas varying from yellowish white to diffuse rose with linear and sharp vessels. 1,3,9 In the case reported, despite the suggestive clinical examination, the evidence of dermoscopic patterns, associated with the presence of hypopyon-like, reinforces the reliability of this method for clinical diagnosis, allowing to rule out the most important differential diagnoses.…”

“…3,8,9 Another dermoscopic pattern consists of colored areas varying from yellowish white to diffuse rose with linear and sharp vessels. 1,3,9 In the case reported, despite the suggestive clinical examination, the evidence of dermoscopic patterns, associated with the presence of hypopyon-like, reinforces the reliability of this method for clinical diagnosis, allowing to rule out the most important differential diagnoses.…”

“…The intensity of the signal may vary according to the composition of the liquid within the vesicles. Histopathological examination is considered gold standard in the diagnosis of CLC, in which vesicles represent dilated lymphatic vessels in the papillary dermis, with the possibility to extend up to the reticular dermis and subcutaneous tissue, with or without hyperkeratosis and irregular acanthosis . The lymphatic lumen is filled with finely granular hyaline material and red blood cells, probably from small capillary shunts…”

Dermoscopy of cutaneous lymphangioma circumscriptum

“…CLC displaying the latter pattern might occasionaly be difficult to discriminate from haemangiomas [2,3]. An additional dermoscopic clue has recently been described as the “hypopyon-like feature.” As sedimentation of blood occurs, its corpuscles aggregate according to their density, with cellular components lying at the bottom and serum at the upper part, resulting in a color transition from dark to light in some lacunae, creating a similar effect to that seen on the eye—the hypopyon [4].…”