Dermoscopic “setting sun” pattern of juvenile xanthogranuloma

Solitary orange papule on the back of a middle-aged man

“…In fully developed lesions, the surrounding erythema decreased, and yellow globules became more evident as the histiocytes transformed to more xanthomatous cells, while in late regressive lesions, prominent whitish streaks were identified and were suggested to correspond to fibrosis [ 5 ]. It was suggested that dermoscopy might be helpful in differentiating JXG from other conditions that appear as solitary yellow-orange lesions [ 6 , 7 ].…”

Is the setting sun dermoscopic pattern specific to juvenile xanthogranuloma?

“…To the Editor: We read with interest the published cases by Pretel et al 1 and by Mun et al 2 describing the setting sun dermoscopic pattern of juvenile xanthogranuloma (JXG). The setting sun dermoscopic pattern is characterized by a yellow-orange background surrounded by erythematous border and is reported to be a characteristic dermoscopic feature of JXG.…”

“…Pretel et al reported that this dermoscopic sign could be helpful for differentiating JXG from similar conditions and recognition of this feature could preclude skin biopsy. 1 We searched PubMed to identify published dermoscopic features of JXG and those of JXG's main differential diagnoses, namely dermatofibroma, Spitz nevus, hemangioma, rhabdomyosarcoma, xanthoma disseminatum, reticulohistiocytoma, benign cephalic histiocytosis, and mastocytoma.…”

Xantogranuloma Juvenil Cutâneo Disseminado: Relato de Caso

“…5 Esse aspecto tem sido considerado como um achado dermatoscópico característico do XGJ, estando presente nas lesões bem estabelecidas mas ausente nas lesões tardias em fase de regressão. 11 Revista SPDV 77 (1) O diagnóstico é confirmado pela histopatologia que mostra um infiltrado misto com histiócitos, linfócitos, eosinófilos, neutrófilos e células plasmáticas que se estendem da derme até à hipoderme, sendo raro o envolvimento epidérmico. 9 Contudo, as características histológicas variam de acordo com a fase evolutiva da lesão, com predomínio de histiócitos grandes, linfócitos e eosinófilos nas lesões recentes enquanto que nas lesões bem estabelecidas podem ser vistas as células gigantes de Touton e nas lesões em involução há mais tecido fibroso.…”