Dermoscopy is useful for the diagnosis of milia‐like idiopathic calcinosis cutis

A solitary lesion of idiopathic calcinosis cutis in an infant: subepidermal nodular calcinosis or milia-like idiopathic calcinosis cutis?

“…In a few reported cases, white structures forming a subtle petaloid appearance have been detected under dermatoscopy. Though white structures are also seen in molluscum contagiosum or milia, it is suggested that the central crust corresponding to the transepidermal elimination of calcinosis may be important for the diagnosis of MICC [5,6]. Our case showed the dermatoscopic features described for MICC, supporting the diagnosis of perforating calcinosis cutis.…”

“…The etiopathogenesis is unclear. Calcium retention in sweat glands, recurrent trauma, or secondary calcification of preexisting microepidermal cysts have been supposed as causative or triggering factors [1,2,5,6]. In our case there was no DS or preceding history of trauma, but we speculate that twin pregnancy might have promoted repeated intrauterine physical trauma.…”

“…They resemble milia and are sometimes surrounded by erythema. Almost always there are multiple lesions that are mainly located on the hands and feet and rarely on the face [1,2,5,6].…”

“…Dermatology Online Journal || Case Presentation confirming that it is calcium. Transepidermal elimination of the calcific deposits may be present [1,2,5,6].…”

Diagnostic aid to subepidermal calcified nodule with dermoscopy and reflectance confocal microscopy: a case report

“…The patient remained recurrence-free for the entire follow-up period (6 months). A round, well-circumscribed lesion with central round cystic areas filled with brightly refractile material [9] The characteristic molluscum bodies [9] Juvenile Xanthogranuloma Setting sun appearance, clouds of paler yellow globules, linear and branched vessels, and whitish streaks [10] Epidermal normal honeycomb pattern, dome-shaped lesion, dilated dermal papillae at dermal-epidermal junction filled with clusters of roundish, large, multinucleated, and hyperrefractile atypical cells corresponding to Touton cells [11] Vacuolated cells, xanthomatized cells, spindle-shaped cells, and oncocytic cells The histiocytic infiltrations in the papillary dermis and the reticular dermis [10] Common Warts Multiple densely packed papillae with a central red dot or loop, surrounded by a whitish halo; hemorrhages [12] Elongated and enlarged dermal papillae containing dilated capillary vessels [6] Elongated and enlarged dermal papillae containing dilated capillary vessels; koilocytes [6] Pilomatrixoma White and/or yellow homogeneous areas shaped and distributed irregularly (corresponding histopathologically to calcification or keratin masses), white streaks, reddish homogeneous areas, hairpin vessels, and linear irregular vessels [13] Not reported Basaloid cells, calcification and ghost (phantom, shadow) cells [14] BCC (MAY) multiple aggregated yellow-white globules [15] A well-defined tumor with hyperreflective amorphous areas [15] Tumor islands with palisading and clefting and calcium deposits [15] MICC round white homogeneous lesions, central crusts [16] Not reported Basophilic materials in superficial dermis [16]…”