Dermoscopy of Squamous Cell Carcinoma and Keratoacanthoma

Rosendahl, Cliff; Cameron, Alan; Argenziano, Giuseppe; Zalaudek, Iris; Tschandl, Philipp; Kittler, Harald

doi:10.1001/archdermatol.2012.2974

Cited by 160 publications

(192 citation statements)

References 23 publications

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“…However, the presence of central keratin favours a diagnosis of keratoacanthoma over squamous cell carcinoma. This finding is crucial as it correlates to a central keratin plug on histopathology of keratoacanthoma [1].…”

Section: Discussionmentioning

confidence: 87%

“…The white mass with central blood spots and keratin crusts along with the characteristic peripheral arrangement of hair pin blood vessels is diagnostic of keratoacanthoma [1]. Also, the peripheral arrangement of hair pin blood vessels favours a diagnosis of keratoacanthoma over seborrheic keratosis in which the hair pin vessels are evenly distributed throughout the lesion [2].…”

Section: Discussionmentioning

confidence: 99%

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Dermoscopic surprises in a series of 6 cases

Malakar¹,

Mehta²,

Mukherjee³

et al. 2018

Our Dermatol Online

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Section: Discussionmentioning

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Dermoscopic surprises in a series of 6 cases

Malakar¹,

Mehta²,

Mukherjee³

et al. 2018

Our Dermatol Online

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“…21,29 Yüksek riskli hastalarda önerilen tedavi yöntemi Mohs cerrahisidir. 21,30,31 Dermatoskopik inceleme, kötü diferansiye skuamöz hücreli karsinomların iyi ve orta diferansiye skuamözden ayrımını sağlayarak tedavi planlamasına yardımcı olabilir. 32 Son yıllarda yapılan çalışmalarda; ultrasonografi (USG), optik koherens tomografi, konfokal mikroskopi, pozitron emisyon tomografi gibi gö-rüntüleme yöntemlerinin NMCK tanısına katkısı araştırılmıştır.…”

Section: Bulgularunclassified

Evaluation of the Cases Who Were Referred to Plastic Surgery Clinic Out of Suspicion of Non-melanoma Skin Cancer Localized at Head and Neck Region in Sivas Numune Hospital

Derebaşınlıoğlu¹,

Özkaya²,

Parlak³

2016

Turkiye Klinikleri J Dermatol

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Ö ÖZ ZE ET T A Am ma aç ç: : Sivas Numune Hastanesi Plastik Cerrahi Polikliniğine baş-boyun bölgesi yerleşimli nonmelanositik cilt kanseri ön tanısıyla konsülte edilen ve eksizyonel biyopsi uygulanan hastalarda yaş, tutulan bölge, lezyon türleri ve kullanılan rekonstrüksiyon tekniklerini belirleyebilmektir. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : 1 Ocak 2013-1 Aralık 2014 tarihleri arasında Sivas Numune Hastanesi Plastik Rekonstrüktif ve Estetik Cerrahi Polikliniğine baş-boyun bölgesine yerleşimli nonmelanositik cilt kanseri ön tanısıyla konsülte edilen 163 hastaya yapılan 176 eksizyonel biyopsinin patolojik sonuçları incelenmiştir. B Bu ul lg gu ul la ar r: : Çalış-mamızda incelenen 163 hastanın 80 (%49,07)'ini erkekler, 83 (%50,9)'ünü ise kadınlar oluşturmakta idi. Ortalama yaş 60,4 olarak tespit edildi. Çalışmaya alınan 176 eksizyonel biyopsi sonucunun 105 (%59,6)'ini bazal hücreli karsinom, 14 (%7,9)'ünü skuamöz hücreli karsinom, 5 (%2,8)'ini bazoskuamöz hücreli karsinom, 25 (%14,2)'ini seboreik keratoz, 6 (%3,4)'sını aktinik keratoz, 18 (%10,2)'ini keratoakantom, 1 (%0,56)'ini rüptüre epidermal kist, 1 (%0,56)'ini inflamasyon, 1 (%0,56)'ini granülasyon dokusu oluştur-makta idi. Nonmelanositik cilt kanserinin en sık görülen lokalizasyonu burun idi. S So on nu uç ç: : Çalışmamızda toplam 163 baş-boyun bölgesine lokalize nonmelanositik cilt kanseri ön tanısyla dermatoloji kliniğinden konsülte edilen hastalardan yapılan 176 eksizyonel biyopsi sonucunda 124 (%70,4) adet nonmelanositik cilt kanseri tespit edilirken, 24 (%13,6) adet premalign lezyon saptanmıştır. En sık görülen nonmelanositik cilt kanseri bazal hücreli karsinom olurken, ikinci sıklıkla skuamöz hücreli karsinom görülmüştür. Sonuç olarak, nonmelanositik cilt kanserleri şüphesi olan lezyonlara %70,4 oranında klinik olarak doğru malignite tanısı konulmuştur.A An na ah h t ta ar r K Ke e l li i m me e l le er r: : Karsinom, bazal hücre; karsinom, skuamöz hücre; baş ve boyun neoplazileri; patoloji A AB BS S T TR RA AC CT T O Ob bj je ec ct ti iv ve e: : We aimed to determine age, gender, localization area and types of lesions and reconstruction tecniques, suspicion of nonmelanoma skin cancer cases who were consulted from dermatology clinic localizated at head and neck. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : Retrospective review of 163 patients undergoing exicion biopsy at the Sivas Numune Hospital Plastic Reconstructive Surgery Clinic for suspicion of nonmelanoma skin cancer localized at head and neck region, between January 2013 and December 2014 was undertaken. 176 excision material of 163 cases were searched. R Re es su ul lt ts s: : In this study 163 patients (80; 49.07% males, 83; 50,9% females) were evaluated. Average of year was 60,4. Of the 175 exision material; 105 (60 %) were basal cell carcinoma, 13 (14.2%) were squamous cell carcinoma, 5 (2.8%) were basosquamous cell carcinoma, 25 (14.2%) were seboreic keratosis, 18 (10.2%) were keratoacanthoma, 6 (3.4%) were actinic keratosis, 1 (0.57%) was ruptured epider...

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“…Keratin crust/scale had the highest sensitivity for keratoacanthoma and SCC (79%) and with circles had the highest specificity (87%). 25 Lin et al 26 have observed white circles in 32% of SCCs and 38% of keratoacanthomas, keratin crust/scale in 90% of SCCs and all of keratoacanthomas and central keratin masses in 32% of SCCs and 88% keratoacanthomas.…”

mentioning

confidence: 98%

“…It is characterized by rapid growth over a few weeks to months, followed by spontaneous resolution over 4-6 months in most cases, but rarely it may progress to invasive carcinoma. Rosendahl et al 25 identified several dermoscopic criteria that help differential keratoacanthoma from SCC and other nonpigmented lesions. The most important dermoscopic clues to keratoacanthoma and SCC are white circles, keratin crust/scale, blood spots, and white structurless zones.…”

mentioning

confidence: 99%

Non-invasive diagnostic techniques in the diagnosis of squamous cell carcinoma

Warszawik-Hendzel

Olszewska

Maj

et al. 2015

J Dermatol Case Rep

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Squamous cell carcinoma is the second most common cutaneous malignancy after basal cell carcinoma. Although the gold standard of diagnosis for squamous cell carcinoma is biopsy followed by histopathology evaluation, optical non-invasive diagnostic tools have obtained increased attention. Dermoscopy has become one of the basic diagnostic methods in clinical practice. The most common dermoscopic features of squamous cell carcinoma include clustered vascular pattern, glomerular vessels and hyperkeratosis. Under reflectance confocal microscopy, squamous cell carcinoma shows an atypical honeycomb or disarranged pattern of the spinous-granular layer of the epidermis, round nucleated bright cells in the epidermis and round vessels in the dermis. High frequency ultrasound and optical coherence tomography may be helpful in predominantly in pre-surgical evaluation of tumor size. Emerging non-invasive or minimal invasive techniques with possible application in the diagnosis of squamous cell carcinoma of the skin, lip, oral mucosa, vulva or other tissues include high-definition optical coherence tomography, in vivo multiphoton tomography, direct oral microscopy, electrical impedance spectroscopy, fluorescence spectroscopy, Raman spectroscopy, elastic scattering spectroscopy, differential path-length spectroscopy, nuclear magnetic resonance spectroscopy, and angle-resolved low coherence interferometry. (J Dermatol Case Rep. 2015; 9(4): 89-97)

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Dermoscopy of Squamous Cell Carcinoma and Keratoacanthoma

Abstract: To characterize dermoscopic criteria of squamous cell carcinoma (SCC) and keratoacanthoma and to compare them with other lesions.

Cited by 160 publications

References 23 publications

Dermoscopic surprises in a series of 6 cases

Dermoscopic surprises in a series of 6 cases

Evaluation of the Cases Who Were Referred to Plastic Surgery Clinic Out of Suspicion of Non-melanoma Skin Cancer Localized at Head and Neck Region in Sivas Numune Hospital

Non-invasive diagnostic techniques in the diagnosis of squamous cell carcinoma

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