Dermoscopy of Vulvar Pigmented Basal Cell Carcinoma

Bertaina, Chiara; Salerni, Gabriel; Celoria, Melisa; Lombardo, Silvina; Gorosito, Mario; Molteni, Ana; Fernández-Bussy, Ramón

doi:10.5826/dpc.0903a20

Cited by 3 publications

(1 citation statement)

References 2 publications

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“…Approximately 66% of patients (18/27) were of Asian ethnicity (Table 1). [2][3][4][5][6][7][8][9][10] Vulvar BCC can sometimes be an aggressive neoplasm with deep local extension and perineural invasion. 11 Two out of 27 (7.4%) pigmented vulvar BCC cases reported either perineural or perivascular invasion and were at least 6 cm at presentation.…”

Section: Discussionmentioning

confidence: 99%

Pigmented vulvar basal cell carcinoma in a Hispanic patient treated with Mohs micrographic surgery

Poppens,

Lee,

Nguyen

2023

International Journal of Women’s Dermatology

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Section: Discussionmentioning

confidence: 99%

Pigmented vulvar basal cell carcinoma in a Hispanic patient treated with Mohs micrographic surgery

Poppens,

Lee,

Nguyen

2023

International Journal of Women’s Dermatology

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Pigmented nonmelanoma skin cancers of the genital area: a diagnostic and therapeutic challenge – monocentric experience and review of the literature

Licata,

Tancredi,

Giorgio

et al. 2024

Int J Dermatology

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Nonmelanoma skin cancers (NMSC), comprising basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are typically encountered on photo‐exposed skin. Nevertheless, several cases of NMSC have been described in covered areas such as the genital region; furthermore, some of these lesions may express a variable degree of pigmentation. Due to the existence of mucosal melanoma, an accurate diagnosis is paramount. In this narrative review, we focused our attention on management and – in particular‐ diagnosis of pigmented NMSC (pNMSC) located in the genital region, emphasizing the features assessed by dermoscopy and reflectance confocal microscopy. As an implementation, we included data on pNMSC from the Dermatology Unit of the University of Campania Vanvitelli. BCC in the genital region represents only 1% of all BCC cases. It has been supposed that the mutation of patched 1 may lead to the development of BCC even without concomitant UV exposure. Pigmented variants on genitals have seldom been described. More prominent dermoscopic features seem to be blue‐gray ovoid nests and arborizing vessels associated with whitish structureless areas. SCC and Bowen's disease (BD) – a variant of in situ SCC – may be encountered in the genital area and are sometimes associated with human papillomavirus (HPV) infection. Pigmented SCC is very rare, and most of the literature is focused on pigmented BD (pBD), which is mainly characterized by gray‐brown dots in a linear fashion and glomerular vessels without evident scales. In conclusion, pNMSC is rarely encountered on genitals; evaluation with dermoscopy or other ancillary devices like RCM is important both to exclude benign lesions like seborrheic keratosis and lentigo and to rule out melanoma.

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Authors’ reply: Comment on: Vulvar basal cell carcinoma: clinical features and treatment outcomes from a tertiary care centre

Namuduri¹,

Lim²,

Yam³

et al. 2020

smedj

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Dermoscopy of Vulvar Pigmented Basal Cell Carcinoma

Cited by 3 publications

References 2 publications

Pigmented vulvar basal cell carcinoma in a Hispanic patient treated with Mohs micrographic surgery

Pigmented vulvar basal cell carcinoma in a Hispanic patient treated with Mohs micrographic surgery

Pigmented nonmelanoma skin cancers of the genital area: a diagnostic and therapeutic challenge – monocentric experience and review of the literature

Authors’ reply: Comment on: Vulvar basal cell carcinoma: clinical features and treatment outcomes from a tertiary care centre

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