Description of Streptomyces neopeptinius sp. nov., an actinobacterium with broad spectrum antifungal activities

Abstract

A streptomycete strain producing broad-spectrum antifungal substances was taxonomically characterized. The strain, designated KNF 2047(T) (= SH-09(T) = KCTC 10586BP(T)), was found to form extensively branching aerial and substrate mycelia, and produce spiny-ornamented spores with loose spiral chains. The whole cell hydrolyzates contained major amount of LL-diaminopimelic acid. The major fatty acids of the phospholipids were saturated and branched fatty acids containing 14~17 carbons, and the major isoprenoid quinones were hexa-and octa-hydrogenated menaquinones with 9 isoprene units. The phylogenetic analysis using the 16S rRNA gene indicated that the strain belongs to the genus Streptomyces but forms an independent phyletic line. These results clearly demonstrate that strain KNF2047(T) forms a new center of taxonomic variation within Streptomyces, for which the name Streptomyces neopeptinius sp. nov. is proposed.

Isolation and characterisation of rhizosphere bacteria active against Meloidogyne incognita , Phytophthora nicotianae and the root knot-black shank complex in tobacco

“…Of the 19 DAB species that were obtained in this study, only three functioned as DAB against previously reported fungal pathogens and plant‐parasitic nematodes, including B. cereus , P. putida and S. flavofungini . Additionally, four species ( B. tequilensis , S. marcescens , S. albidoflavus and S. neopeptinius ) produced antifungal compounds, whereas the other four species ( B. drentensis , S. marcescens subsp. sakuensis , B. diminuta and S. alboflavus ) exhibited nematicidal activity.…”

Structural diversity, biosynthesis, and biological functions of lipopeptides fromStreptomyces

“…134 Neopeptins A and B also displayed potent therapeutic ability and protective activity against powdery mildew disease. 135,136…”

Antimicrobial Cyclic Peptides for Plant Disease Control

“…The growth of Glomerella cingulata , P. oryzae , Cochliobolus miyabeanus, and Colletotrichum lagenaium can be completely inhibited by neopeptins at a concentration of 4 μg/ml. In one study, the development of powdery mildew on cucumber plants was effectively controlled by a mixture of neopeptins isolated from a culture of Streptomyces neopeptinius (Han et al, 2008; Kim et al, 2007). The tyrocidines (Fig.…”