Description of the Entropy™ algorithm as applied in the Datex‐Ohmeda S/5™ Entropy Module

Viertiö-Oja, H.; Maja, V; Särkelä, Mika O. K.; Talja, Pia; Tenkanen, N; Tolvanen-Laakso, Heli; Paloheimo, Markku; Vakkuri, Anne; Yli‐Hankala, Arvi; Meriläinen, Pekka

doi:10.1111/j.0001-5172.2004.00322.x

Cited by 513 publications

(392 citation statements)

References 10 publications

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“…Second, the Shannon function is applied to assign each frequency a specific value. The exact algorithm has been described in detail elsewhere [8]. In contrast to other cerebral monitoring devices, the M-entropy module digitizes the EEG at a much higher sampling rate (400Hz) and, to detect artefacts, the power in the frequency range (200 -1000 kHz) is continuously measured, The M-entropy module generates two distinct numbers for response entropy (RE) and state entropy (SE) between 100 to 0 and 91 to 0, respectively.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Spectral Entropy and Bispectral Index Electroencephalography in Coronary Artery Bypass Graft Surgery

Baulig

Seifert

Schmid

et al. 2010

Journal of Cardiothoracic and Vascular Anesthesia

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Objective: The study's aim was to compare Response (RE) and State Entropy (SE) with Bispectral Index (BIS) electroencephalography (EEG) as an alternative cerebral monitoring tool in patients scheduled for coronary artery bypass graft surgery.Design: Prospective, observational single-center study Setting: University HospitalParticipants: Thirty patients undergoing coronary artery bypass graft surgery receiving remifentanil-propofol anaesthesia.Interventions Surgery was performed with cardiopulmonary bypass (CPB) and cardiac arrest in fifteen patients, with CPB without cardiac arrest in nine patients and without CPB in six patients. Measurements and Main results RE, SE, BIS, burst suppression ratio (BSR) and frontalelectromyography (f-EMG) were detected simultaneously. RE and SE compared favorably to BIS and their correlations were strong (r 2 = 0.6, r 2 = 0.55, respectively). Mean bias of RE and BIS was -1.8, but limits of agreement were high (+20.5/-24.1). RE and SE tended to be lower than the BIS values in the CPB subgroups. Detection of BSR was similar with RE and SE, and the BIS. A strong correlation existed between BIS and f-EMG (r 2 = 0.62), in contrast to RE (r 2 = 0.45) and SE (r 2 =0.39). BIS monitoring was significantly more disturbed than RE and SE with 9.1 ±10.9% and 0.1±0.2% of the total anesthesia time, respectively. Neither implicit nor explicit memory was demonstrated.Conclusion RE and SE are comparable with the BIS but showed significantly less interference from f-EMG and superior resistance against artefacts. Thus, Spectral Entropy is more suitable than the BIS during propfol-remifentanil anesthesia in cardiac surgery patients. Words: 2482

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Section: Introductionmentioning

confidence: 99%

Comparison of Spectral Entropy and Bispectral Index Electroencephalography in Coronary Artery Bypass Graft Surgery

Baulig

Seifert

Schmid

et al. 2010

Journal of Cardiothoracic and Vascular Anesthesia

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“…The response entropy value is always higher or equal to the state entropy value. A comprehensive description of the calculation algorithm of state and response entropy has recently been published [9]. Several studies have validated the ability of entropy to measure the hypnotic component of anaesthesia with either volatile or intravenous anaesthetics [10][11][12][13].…”

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confidence: 99%

M‐Entropy guidance vs standard practice during propofol‐remifentanil anaesthesia: a randomised controlled trial*

et al. 2007

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SummarySeventy-two patients undergoing routine surgical procedures under propofol-remifentanil anaesthesia were randomly assigned to receive either standard clinical practice (n = 35) or standard practice plus monitoring of depth of anaesthesia with M-Entropy (n = 37). Patients in the standard practice group received more propofol than the entropy group (mean (SD) 95 (14) vs 81 (22) lg.kg )1 .min )1 , respectively; p < 0.01), and less remifentanil (0.39 (0.08) vs 0.46 (0.08) lg.kg )1 .min )1 , respectively; p < 0.001). Loss of consciousness was best predicted by BIS (prediction probability (P K ) 0.96) and response entropy (P K 0.93), whereas emergence was best predicted by response entropy (P K 0.94).

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“…The RE-SE difference represents FEMG activity. 2,3 Neuromuscular blockade has no effect on SE, but RE decreases to nearly the same value as SE. RE and SE stays the same until neuromuscular blockade has worn off.…”

Section: Hw Van Rooyen Backgroundmentioning

confidence: 97%

The relationship between intra-operative entropy of the EEG and non-depolarizing neuromuscular blockade: A descriptive study

Rooyen¹

2006

Southern African Journal of Anaesthesia and Analgesia

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Description of the Entropy™ algorithm as applied in the Datex‐Ohmeda S/5™ Entropy Module

Cited by 513 publications

References 10 publications

Comparison of Spectral Entropy and Bispectral Index Electroencephalography in Coronary Artery Bypass Graft Surgery

Comparison of Spectral Entropy and Bispectral Index Electroencephalography in Coronary Artery Bypass Graft Surgery

M‐Entropy guidance vs standard practice during propofol‐remifentanil anaesthesia: a randomised controlled trial*

The relationship between intra-operative entropy of the EEG and non-depolarizing neuromuscular blockade: A descriptive study

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