Descriptive and Longitudinal Observations  on the Relationship of Borderline Personality  Disorder and Bipolar Disorder

Gunderson, John G.; Weinberg, Igor; Daversa, Maria T.; Kueppenbender, Karsten; Zanarini, Mary C.; Shea, M. Tracie; Skodol, Andrew E.; Sanislow, Charles A.; Yen, Shirley; Morey, Leslie C.; Grilo, Carlos M.; McGlashan, Thomas H.; Stout, Robert L.; Dyck, Ingrid R.

doi:10.1176/ajp.2006.163.7.1173

Cited by 130 publications

(90 citation statements)

References 25 publications

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“…The SCID-I is a researcher-administered interview schedule that assesses symptoms of various psychiatric conditions including bipolar disorder (mania, hypomania, depression, and psychotic symptoms), major depressive disorder (single episode and recurrent), and dysthymia. Diagnostic reliability of the SCID-I for DSM-IV criteria for bipolar disorder has been reported with a kappa value of 0.74 (27). ii) Young Mania Rating Scale (YMRS) (28).…”

Section: Participantsmentioning

confidence: 99%

A randomized controlled trial of mindfulness‐based cognitive therapy for bipolar disorder

Perich

Manicavasagar

Mitchell

et al. 2012

Acta Psychiatr Scand

116

118

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A randomized controlled trial of mindfulness-based cognitive therapy for bipolar disorder.Objective: To compare the efficacy of mindfulness-based cognitive therapy (MBCT) plus treatment as usual (TAU) to TAU alone for patients with bipolar disorder over a 12-month follow-up period. Method: Participants with a DSM-IV diagnosis of bipolar disorder were randomly allocated to either MBCT plus TAU or TAU alone. Primary outcome measures were time to recurrence of a DSM-IV major depressive, hypomanic or manic episode; the Montgomery-Å sberg Depression Rating Scale (MADRS); and Young Mania Rating Scale (YMRS). Secondary outcome measures were number of recurrences, the Depression Anxiety Stress Scales (DASS), and the State Trait Anxiety Inventory (STAI). Results: Ninety-five participants with bipolar disorder were recruited to the study (MBCT = 48; TAU = 47). Intention-to-treat (ITT) analysis found no significant differences between the groups on either time to first recurrence of a mood episode or total number of recurrences over the 12-month period. Furthermore, there were no significant betweengroup differences on the MADRS or YMRS scales. A significant between-group difference was found in STAI -state anxiety scores. There was a significant treatment by time interaction for the DASachievement subscale. Conclusion: While MBCT did not lead to significant reductions in time to depressive or hypo/manic relapse, total number of episodes, or mood symptom severity at 12-month follow-up, there was some evidence for an effect on anxiety symptoms. This finding suggests a potential role of MBCT in reducing anxiety comorbid with bipolar disorder. Significant outcomes T. Perich• Mindfulness-based cognitive therapy (MBCT) significantly improved state anxiety for those diagnosed with bipolar disorder over a 12-month follow-up period.• Improvements were found in reducing dysfunctional attitudes surrounding ideas of achievement for those allocated to MBCT. Limitations• The small sample size and high drop-out rate over the 12-month follow-up period.• A shorter follow-up period than other published trials of MBCT. 333

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Section: Participantsmentioning

confidence: 99%

A randomized controlled trial of mindfulness‐based cognitive therapy for bipolar disorder

Perich

Manicavasagar

Mitchell

et al. 2012

Acta Psychiatr Scand

116

118

View full text Add to dashboard Cite

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“…The disruption of attachment (the neurobiological underpinning of relationships) or their inevitable transformations leads these patients to more depression or as a defense have manic/ hypomanic episodes. In the latter situation, there is a tendency to confirm, at least theoretically Kleinian hypothesizes the occurrence of mania as a defense against depression and object dependency [18,19,32,33] anticipates this configuration and its relationship to the blues. He considers three fundamental premises in this condition: 1) object loss; 2) ambivalence; and 3) the regression of the libido to the self.…”

Section: Discussionmentioning

confidence: 99%

“…He proposed a narcissistic type of relationship with the object, which now may apply to patients from cluster B (American Psychiatric Association, 1994) [1]. Freud seemed to relate melancholy with obsessional neurosis due to the degree of ambivalence present in both conditions and referred to it as " obsessive depression" [19].…”

Section: Introductionmentioning

confidence: 99%

Can Research Confirm Psychopathological Subtypes and Relationship between Recurrent Mood Disorders and Personality Disorders?

Corral¹

2015

J Sleep Disord Ther

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The aim of this study is to estimate the frequency of personality disorders in patients with recurrent unipolar or bipolar affective disorders and the possible relationship of the categorical model with two dynamic psychopathological configurations. Forty-eight patients were studied using semi-structured interviews for assessing Axis I and Axis II disorders. We found that approximately 70% of patients had some types of personality disorder according to the DSM-IV TR classification model. The most frequent personality disorders were cluster C dependent personality disorder and cluster B borderline personality disorder. The most common affective disorders were depressive bipolar I subtype disorder and manic bipolar I subtype disorder. The high frequency of personality disorders in patients who are in partial or complete remission of recurrent affective disorders can be explained by a combination of two subtypes of psycho-pathological configurations (the anaclitic or introjective configurations are based on the Blatt model) and neuro-biological interactions.

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“…Although there is some comorbidity with bipolar-II, most cases are distinct, and these disorders do not overlap when patients are followed over time (Gunderson et al, 2006;Paris, Gunderson, & Weinberg, 2007). BPD patients also respond inconsistently to treatment with mood stabilizers (Paris, 2008a), and most of the impact of mood stabilizers is limited to symptoms of anger/impulsivity (Mercer, Douglass, & Links, 2009).…”

Section: Why Bpd Is Not a Mood Disordermentioning

confidence: 99%

The case for retaining borderline personality disorder as a psychiatric diagnosis

Paris

Silk

Gunderson

et al. 2009

Personality & Mental Health

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Descriptive and Longitudinal Observations on the Relationship of Borderline Personality Disorder and Bipolar Disorder

Cited by 130 publications

References 25 publications

A randomized controlled trial of mindfulness‐based cognitive therapy for bipolar disorder

A randomized controlled trial of mindfulness‐based cognitive therapy for bipolar disorder

Can Research Confirm Psychopathological Subtypes and Relationship between Recurrent Mood Disorders and Personality Disorders?

The case for retaining borderline personality disorder as a psychiatric diagnosis

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