Design and Compressive Fatigue Properties of Irregular Porous Scaffolds for Orthopedics Fabricated Using Selective Laser Melting

Zhu, Lei; Liang, Huixin; Lv, Fei; Xie, Dexin; Wang, Changjiang; Mao, Yuyi; Yang, Youwen; Tian, Zongjun; Shen, Lida

doi:10.1021/acsbiomaterials.0c01392

Cited by 25 publications

(12 citation statements)

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“…Structural characteristics and mechanical parameters of the two scaffolds obtained from the compressive test and response surface prediction are listed in Table . The results showed that positive and negative deviations between predicted and test values are both less than 10%. , As a result, model regression equations can accurately predict structural characteristics and mechanical parameters of scaffolds when unit cell design factors are V ϵ [3, 9], F 1 ϵ [0.2, 0.6], and F 2 ϵ [0.2, 0.6].…”

Section: Resultsmentioning

confidence: 95%

“…Irregular porous scaffolds designed using Voronoi tessellation exhibited a certain degree of randomness that resulted in large processing deviations according to distributions of random points because local pore and strut diameters failed to meet manufacturing requirements from the perspective of design. , Local modeling was used as the main method, and the Voronoi unit cell was established using three independent design factors in this study. The unit cell structure divided by the equal volume of Voronoi was anisotropic, that is, the unit cell structure had different structural properties in planes XOY, YOZ, and XOZ.…”

Section: Discussionmentioning

confidence: 99%

“…The results showed that positive and negative deviations between predicted and test values are both less than 10%. 19,46 As a result, model regression equations can accurately predict structural characteristics and mechanical parameters of scaffolds when unit cell design factors are V ϵ [3,9], F 1 ϵ [0.2, 0.6], and…”

Section: Prediction and Analysis Of The Performance Parameters Of Mul...mentioning

confidence: 99%

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Additively Manufactured Multilevel Voronoi-Lattice Scaffolds with Bonelike Mechanical Properties

Zou

Gong

Gao

2022

ACS Biomater. Sci. Eng.

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Irregular porous scaffold through Voronoi tessellation based on global modeling demonstrated randomness to a certain degree and susceptibility to producing large processing deviations. A modeling method for new types of scaffolds based on periodic arrays of Voronoi unit cell was proposed in this study. These porous scaffolds presented controllable local cells and satisfactory mechanical properties. The topological structure of the Voronoi unit cell was controlled using three independent cell design factors (Voronoi polyhedron volume V, face-centered scaled factor F 1, and body-centered scaled factor F 2), and multilevel Voronoi-lattice scaffolds were constructed on the basis of periodic arrays of the Voronoi unit cell. Compressive test and simulation were combined to quantify the mechanical properties of scaffolds. The regression equations were established using the response surface method (RSM) to determine relationships between Voronoi unit cell design factors and structural characteristic parameters and mechanical properties. The same trends were observed in stress–strain curves of the compressive test and simulation. The mechanical properties of scaffolds can be appropriately quantified via simulation. Regression equations based on RSM can properly predict the structural characteristic parameters and mechanical properties of the scaffold. Compared with V, F 1 and F 2 exerted a stronger influence on the structural characteristic parameters and mechanical properties of the scaffold. The modeling method of the multilevel Voronoi-lattice scaffold based on the Voronoi unit cell was proposed in this study to design the porous scaffold and meet the requirements of human bone morphology, mechanical properties, and actual manufacturing by adjusting factors V, F 1, and F 2. The proposed method can provide a feasible strategy for designing implants with suitable and similar morphologies and mechanical properties to cancellous bone.

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Section: Resultsmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

Section: Prediction and Analysis Of The Performance Parameters Of Mul...mentioning

confidence: 99%

See 1 more Smart Citation

Additively Manufactured Multilevel Voronoi-Lattice Scaffolds with Bonelike Mechanical Properties

Zou

Gong

Gao

2022

ACS Biomater. Sci. Eng.

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“…It requires CT scanning of bone tissue to obtain the 3D structure of bone trabeculae, which are then rotated, stitched, and superimposed to achieve the overall design of the pore structure ( Cheng et al, 2014 ). Alternatively, by employing Voronoi structures, it generates randomly distributed points within the spatial structure under certain conditions in a functional manner, subsequently forming pore structures with unspecified arrangements by connecting points to points ( Deering et al, 2021 ; Zhao et al, 2021 ; Zhu et al, 2021 ). In addition to the above structures, the gradient pore structure has gradually become a research hotspot in recent years as the knowledge of the pore structure of bioengineered porous bone tissue materials has gradually deepened.…”

Section: Introductionmentioning

confidence: 99%

Definition, measurement, and function of pore structure dimensions of bioengineered porous bone tissue materials based on additive manufacturing: A review

Wen

Liu

Wang

2023

Front. Bioeng. Biotechnol.

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Bioengineered porous bone tissue materials based on additive manufacturing technology have gradually become a research hotspot in bone tissue-related bioengineering. Research on structural design, preparation and processing processes, and performance optimization has been carried out for this material, and further industrial translation and clinical applications have been implemented. However, based on previous studies, there is controversy in the academic community about characterizing the pore structure dimensions of porous materials, with problems in the definition logic and measurement method for specific parameters. In addition, there are significant differences in the specific morphological and functional concepts for the pore structure due to differences in defining the dimensional characterization parameters of the pore structure, leading to some conflicts in perceptions and discussions among researchers. To further clarify the definitions, measurements, and dimensional parameters of porous structures in bioengineered bone materials, this literature review analyzes different dimensional characterization parameters of pore structures of porous materials to provide a theoretical basis for unified definitions and the standardized use of parameters.

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“…The authors found that the built struts were larger than the designed thickness, and the struts of 0q were thicker than the struts of 90q. Zhu et al conducted a fatigue test on porous scaffolds and found that the fatigue property was greatly affected by the porosity and heat treatment process [7]. However, there is a lack of research work on the stress concentration in the porous structures from additive manufacturing.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the Porous Structures from Laser Powder Bed Fusion Additive Manufacturing

Wang¹,

Hazlehurst²,

Arjunan³

et al. 2021

Advances in Transdisciplinary Engineering

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Open and closed porous structures with lattice and honeycomb geometry can be built using laser powder bed fusion additive manufacturing processes. The porous structures can be used to tailor the mechanical properties of a component or provide other functionality, such as for bone ingrowth in medical implants. Porous structures were created and analysed in this paper both physically and using finite element modelling. It was found that the accuracy of the built parts was reasonable and within the manufacturing processes general tolerance of +/- 50 μm. However, it was noticeable that the corners of the square shape pores were naturally filleted by the manufacturing process. The finite element model was developed using ANSYS software, stress concentrations were observed in the porous structures under loading. In addition to this, fragments of the material were present on the internal surfaces of the pores, which were formed from partially melted powder particles.

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Design and Compressive Fatigue Properties of Irregular Porous Scaffolds for Orthopedics Fabricated Using Selective Laser Melting

Cited by 25 publications

References 50 publications

Additively Manufactured Multilevel Voronoi-Lattice Scaffolds with Bonelike Mechanical Properties

Additively Manufactured Multilevel Voronoi-Lattice Scaffolds with Bonelike Mechanical Properties

Definition, measurement, and function of pore structure dimensions of bioengineered porous bone tissue materials based on additive manufacturing: A review

Analysis of the Porous Structures from Laser Powder Bed Fusion Additive Manufacturing

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