Design and dynamic characterization of “single-stroke” peristaltic PDMS micropumps

Abstract

In this paper, we present a monolithic PDMS micropump that generates peristaltic flow using a single control channel that actuates a group of different-sized microvalves. An elastomeric microvalve design with a raised seat, which improves bonding reliability, is incorporated into the micropump. Pump performance is evaluated based on several design parameters—size, number, and connection of successive microvalves along with control channel pressure at various operating frequencies. Flow rates ranging 0–5.87 μL min−1 were observed. The micropump design demonstrated here represents a substantial reduction in the number of/real estate taken up by the control lines that are required to run a peristaltic pump, hence it should become a widespread tool for parallel fluid processing in high-throughput microfluidics.

Combined experimental and numerical simulation study of PDMS pneumatic micropumps

“…The frequency at which the peak flow rate is observed is referred to as the optimal frequency. These results of flow rate variation with respect to pneumatic actuation frequency, with a peak flow rate at an optimal frequency, are similar to some of the previously reported pneumatic micropumps [8]. A maximal flow rate of type A micropump is 195 µL/min is achieved at the driving frequency of 35 Hz and applied pressure of 15 psi.…”

A reliable and programmable acoustofluidic pump powered by oscillating sharp-edge structures

“…1-3 These microfluidic pumps, based on their driving mechanisms, can be generally divided into two categories: passive pumps 4-6 and active pumps. 7-9 Passive pumps, particularly the surface-tension based microfluidic pumps, 10,11 allow the manipulation of fluids without the need of peripheral equipment or moving parts, making them suitable to many portable analytical devices.…”

Laser activated single-use micropumps

“…The revolutionary Quake valve technology, based on pneumatic actuation, has been used to fabricate embedded micropumps [2]. Peristaltic action has also been used with normally open [3] or normally closed [4] architecture for rectangular profile channels, while single stroke systems have been developed [5,6] in an effort to reduce the number of actuators per micropump. Piezoelectric elements [7,8] and Braille pins [9] have been used as actuators in the same manner.…”