Design and evaluation of galactosylated chitosan/graphene oxide nanoparticles as a drug delivery system

Graphenic Materials for Biomedical Applications

“…Figure 12 shows the preparation of a galactosylated-CS/GO/DOX complex. [145]. cells, including pancreatic, breast, gastric, and prostate cancer, as well as hepatocellular and skin squamous cell carcinomas.…”

“…Figure 12 shows the preparation of a galactosylated-CS/GO/DOX complex. [145]. New hydrogel NC films with anti-tumor effects were designed by incorporating GQDs into a carboxymethylcellulose hydrogel and using DOX as a model drug.…”

“…Schematic representation of the synthesis of galactosylated chitosan (CS) and the fabrication of galactosylated-CS/GO/DOX nanoparticles. Reprinted from[145] with permission from Elsevier, copyright 2019.…”

Functional Graphene Oxide Nanocarriers for Drug Delivery

“…In view of these advantages, nanocarriers including nanoparticles, vesicles, nanosheets, and nanocapsules have been intensively investigated in the biomedical field [1][2][3][4][5][6][7][8][9]. As a member of the nanocarrier, graphene oxide (GO) was also focused in the biomedical field on account of the large specific surface area, mechanical properties, and very high aspect ratio [4,[10][11][12][13][14][15]. Especially, the π-conjugated structure of GO could conjugate with a number of drug molecules either through π − π stacking interaction or through chemical covalent crosslinking [4,[10][11][12][13][14][15].…”

“…As a member of the nanocarrier, graphene oxide (GO) was also focused in the biomedical field on account of the large specific surface area, mechanical properties, and very high aspect ratio [4,[10][11][12][13][14][15]. Especially, the π-conjugated structure of GO could conjugate with a number of drug molecules either through π − π stacking interaction or through chemical covalent crosslinking [4,[10][11][12][13][14][15]. However, pure GO lacks a bioactive site to support cell growth, which restricted its application in the biomedical field.…”