2018
DOI: 10.46624/ajptr.2018.v8.i4.027
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Design and Evaluation of Sustained Release Matrix Tablets of Antihyperlipidemic Drug

Abstract: The aim of present work was to design and evaluate sustained release matrix tablets of antihyperlipidemic drug. In the present investigation, polymers used in different combinations such as Eudragit RL100 and HPMC E5 in the ratio of 1:1, 1:2, 1:3 and vice versa with PVP K25 using direct compression technique were prepared. The tablets were evaluated for physical parameters like thickness, hardness, friability, weight variation, and in vitro release studies. The FTIR study indicated that the drug is stable in f… Show more

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