Design and exploration of caffeine-based Brönsted acidic ionic liquid (CaffBAIL) for the synthesis of DHPMs, xanthenediones, and acridinediones

Greening up organic reactions with caffeine: applications, recent developments, and future directions

“…CaffBAIL was also employed for the synthesis of 1,8-dioxooctahydroxanthene derivatives 69 by reaction of dimedone 22 with various aldehydes 68 in 1 : 2 molar ratio by Hataminejad and co-workers. 50 …”

The Synthesis of Nitrogen- and Oxygen-Containing Heterocyclic Scaffolds Assisted by Ionic Liquids: A 2022 Literature Survey

“…The catalytic activity of a novel caffeine-based Bronsted acidic ionic liquid (CaffBAIL) was reported by Ezabadi and co-workers for the synthesis of dihydropyrimidinones 174, in yields of 77-94%, under solvent-free conditions from ethyl acetoacetate (173), urea (112) and substituted benzaldehydes 1 (Scheme 59). 129 The white-colored powdered IL CaffBAIL was synthesized from caffeine and 1,4-butane sultone, and characterized using FT-IR, NMR ( 1 H and 13 C), XRD, FE-SEM, TGA and DTG. Further, the catalytic activity of Caff-BAIL was also explored for the synthesis of xanthendiones, and acridinediones.…”

“…Unauthorized distribution is strictly prohibited. catalyzed by 1-methylimidazolium chloride using isatin (128), malononitrile (18), and barbituric acid (129, Scheme 42). Under microwave irradiation, the reaction was found to proceed with faster rate in higher yields as compared to conventional conditions.…”

“…The catalytic activity of novel caffeine-based Bronsted acidic ionic liquids (CaffBAIL) was reported by Ezabadi and co-workers for the of dihydropyrimidinones (174, Scheme 59)under solvent free conditions from ethyl acetoacetate (173), urea (112) and substituted benzaldehyde (1) in 77-94% yields. 128 The white coloured powdered ILs, CaffBAIL was synthesized from caffeine and 1,4-butane sultone and This article is protected by copyright. All rights reserved.…”