Design and fabrication of an optical probe with a phase filter for extended depth of focus

Xing, Jingchao; Kim, Junyoung; Yoo, Hongki

doi:10.1364/oe.24.001037

Cited by 41 publications

(14 citation statements)

References 22 publications

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“…Various beam shaping methods have been successfully employed for EDF imaging, which involve different amplitude, phase or combined filters in the pupil plane [3][4][5], and in some cases also feature specialized optical elements such as axicons [6,7]. Their implementation typically requires significant changes to a conventional microscope [1].…”

Section: Introductionmentioning

confidence: 99%

Extended depth of focus multiphoton microscopy via incoherent pulse splitting

Chen

Chakraborty

Daetwyler

et al. 2020

Preprint

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We present a phase mask that can be easily added to any multi-photon raster scanning microscope to extend the depth of focus five-fold at a small loss in lateral resolution. The method is designed for ultrafast laser pulses or other light-sources featuring a low coherence length. In contrast to other methods of focus extension, our approach uniquely combines low complexity, high light-throughput and multicolor capability. We characterize the point-spread function in a two-photon microscope and demonstrate fluorescence imaging of GFP labeled neurons in fixed brain samples as imaged with conventional and extended depth of focus two-photon microscopy.

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Section: Introductionmentioning

confidence: 99%

Extended depth of focus multiphoton microscopy via incoherent pulse splitting

Chen

Chakraborty

Daetwyler

et al. 2020

Preprint

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“…Recently, a large number of papers dealing with the design of long optical needles using high numerical aperture (NA) systems have been published [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. This topic has attracted the attention of many groups because of potential applications in imaging, lithography or particle acceleration among others [18][19][20].…”

Section: Introductionmentioning

confidence: 99%

Modeling axial irradiance distortion in holographic optical needles produced with high numerical aperture lenses

et al. 2019

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Optical needles produced by means of diffractive technology might display limited quality and uniformity. It has been suggested that the bulky optical elements present on these setups can be responsible of such behavior. In particular, issues such as the lack of flatness of the optical components, modulation errors in the holographic displays and optical aberrations might degrade the quality of the needle. In this paper we model how these variables affect the uniformity of the irradiance of the needle on the propagation axis. A comparison between experimental and computationally estimated results is provided.

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“…Most designs proposed for generating optical needles are based on the utilization of binary or ternary ring-geometry modulation functions [1]- [6]. Nevertheless, diffractive needles produced by means of high numerical aperture objective lenses usually display remarkable distortions and lack of quality.…”

Section: Introductionmentioning

confidence: 99%

Considerations on the design of diffractive optical needles

Martı́nez-Herrero

Maluenda

Juvells

et al. 2018

2018 17th Workshop on Information Optics (WIO)

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According to intensity consideration along the propagation axis, we derived mathematical conditions for a family of modulating functions able to produce needles of arbitrary length, sub-wavelength width and almost constant irradiance. These functions are derived by introducing mathematical constrains on the on-axis power content. As a result, the modulating distribution is continuous with no jumps within or at the edge of the pupil. Numerical results suggests that the proposed approach is suitable for producing high quality needles.

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Design and fabrication of an optical probe with a phase filter for extended depth of focus

Cited by 41 publications

References 22 publications

Extended depth of focus multiphoton microscopy via incoherent pulse splitting

Extended depth of focus multiphoton microscopy via incoherent pulse splitting

Modeling axial irradiance distortion in holographic optical needles produced with high numerical aperture lenses

Considerations on the design of diffractive optical needles

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