2023
DOI: 10.21203/rs.3.rs-3302884/v1
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Design, and Green synthetic approach of the Aryl-tetrazolo-[1,5-a][1,8]naphthyridine Molecules and their in vitro anti-microbial activity  and In silico molecular modeling studies

Banoth Sonyanaik,
Dharavath Ravi,
Perugu Shyam
et al.

Abstract: An efficient eco-friendly construction of 4-aryltetrazolo [1,5-a][1, 8]naphthyridine scaffolds has been successfully prepared through the microwave method in a short reaction time with good yields. The microwave method has unique advantages, short reaction time, easy workup procedure, and simple purification of the products. Synthesized entire molecules were evaluated for their antimicrobial activity among them compounds 6g and 6a revealed the highest anti-microbial activity. Moreover, in silico molecular mode… Show more

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